BACKGROUND AND OBJECTIVES Uremic metabolic acidosis is only partially corrected in many hemodialysis patients, and low serum bicarbonate predicts higher death risk. This study determined the comparative efficacy of peritoneal dialysis in correcting uremic metabolic acidosis and the association of serum bicarbonate and death risk with the two therapies. DESIGN, SETTING, PARTICIPANTS, & MEASURE...

Mequindox (MEQ) is a synthetic antimicrobial agent widely used in China since the 1980s. Although the toxicity of MEQ is well recognized, its testis toxicity has not been adequately investigated. In the present study, we provide evidence that MEQ triggers oxidative stress, mitochondrion dysfunction and spermatogenesis deficiency in mice after exposure to MEQ (0, 25, 55, and 110 mg/kg in the die...

Hospital Physician January 2009 23 Hyponatremia represents an abnormal ratio of total body sodium to water and is commonly defined as a plasma sodium concentration less than 135 mEq/L (1 mEq/L = 1 mmol/L).1–7 Hyponatremia is the most common electrolyte abnormality in hospitalized patients, with mild hyponatremia (plasma sodium < 135 mEq/L) present in approximately 15% to 22% of patients, modera...

Purpose, The present article was built on the assumption that the form of an examination may influence learning, and may also reflect different kinds of knowledge. The aim of the study was to evaluate whether the results of an examination differ when short answer questions (SAQ) or modified essay questions (MEQ) are used. Method, Forty-nine students in the internal medicine course in Gothenburg...

Marek's disease virus (MDV) is one of the most oncogenic herpesviruses and induces T lymphomas in chickens within weeks after infection. Only a limited number of viral transcripts are detected in MDV tumor samples and cell lines. One of the major transcripts encodes MEQ, a 339-amino-acid bZIP protein which is homologous to the Jun/Fos family of transcription factors. The C-terminal half of MEQ ...

As a major source of water for irrigation, the evaluation and assessment groundwater to ensure it meets quality sustainable agriculture is key. This research presents findings its suitability irrigation purposes. was carried out using indices Geographic Information System (GIS). The Inverse Distance Weighted (IDW) method GIS used study spatial distribution these indices. Indices considered incl...

On October 5, 2005, an 80-year-old woman with no contributory past history consulted our hospital with a complaint of headache. Laboratory studies showed serum sodium of 119 mEq/l and potassium of 4.6 mEq/l. Urinary excretion of sodium was 61 mEq/l. Blood urea nitrogen was 11 mg/dl;serum creatinine, 0.5 mg/dl;serum uric acid, 2.0 mg/dl;and hematocrit, 38.0%. The plasma osmolality was low at 247...

Serotype 1 strains of Marek's disease virus (MDV-1) cause malignant lymphomas in chickens (Marek's disease; MD). Although MD has been controlled by vaccination, field isolates of MDV-1 have tended to increase in virulence and cause MD even in vaccinated chickens. Meq, a putative MDV-1 oncoprotein, resembles the Jun/Fos family of basic leucine zipper (bZIP) transcription factors and can regulate...

Abstract Background and Objectives Conventional hemodialysis (HD) for kidney failure patients with severe hyponatremia may be complicated by rapid correction of hyponatremia, which increases the risk osmotic demyelination syndrome. A simple sodium kinetic equation was effective in prediction end-dialysis serum Na + severely hyponatremic patient treated continuous venovenous hemofiltration, but ...