It is well known that both local and volatile anesthetics depress myocardial functions. This study was performed to evaluate the combined effects of commonly utilized local anesthetics (bupivacaine, mepivacaine, and lidocaine) and a volatile anesthetic (isoflurane) on heart rate and myocardial contractility in an isolated rat working heart preparation using each local anesthetic at 0 to 3 x 10(...

Inferior alveolar nerve block has a high failure rate in the treatment of mandibular posterior teeth with irreversible pulpitis. The aim of this study was to compare the anesthetic efficacy of 4% articaine, 2% lidocaine and 2% mepivacaine, all in combination with 1:100,000 epinephrine, in patients with irreversible pulpitis of permanent mandibular molars during a pulpectomy procedure. Sixty-six...

AIM To assess the efficacy and safety of an intraoperative intracameral injection of mepivacaine, administered when patients experienced pain during the course of cataract surgery under topical anaesthesia. METHODS This is a prospective placebo controlled double masked randomised clinical trial. 50 eyes were included; 25 receiving the active compound and 25 receiving placebo. Mepivacaine (2%,...

BACKGROUND The goal of this in vitro study was to investigate the effects of lipid emulsion (LE) on local anesthetic levobupivacaine-induced responses in isolated rat aorta and to determine whether the effect of LE is related to the lipid solubility of local anesthetics. METHODS Isolated rat aortic rings were suspended for isometric tension recording. The effects of LE were determined during ...

The aim of this study was to evaluate the anesthetic efficacy 4% articaine by buccal infiltration technique (BI) after inferior alveolar nerve block (IANB) with 2% mepivacaine, both 1:100,000 epinephrine, in urgency treatment mandibular molars symptomatic irreversible pulpitis (SIP). This a prospective study, randomized, blinded, controlled parallel clinical trial experimental design. Thirty pa...

Several studies have reported transient neurological symptoms after spinal anaesthesia with 5% lignocaine. In order to evaluate the role of concentrated solutions of local anaesthetic in the development of transient neurological symptoms, 200 ASA I or II patients undergoing minor orthopaedic or rectal surgery under spinal anaesthesia were allocated randomly to receive 4% mepivacaine 80 mg or hy...

CASE REPORT: Over the past decade, liposuction has become the most frequently performed procedure in aesthetic plastic surgery in many countries although it should not be considered without complications. Tumescent local anesthesia is subcutaneous infiltration of very dilute lidocaine and epinephrine to produce subcutaneous swelling. Mepivacaine has never been mentioned to be used in this kind ...

BACKGROUND The multiple injection technique for axillary block, in which the four distal nerves of the plexus are located by a nerve stimulator and separately injected, has been shown to provide a high success rate and a short onset time. This randomized double-blind study was conducted to compare the effectiveness of three different volumes of mepivacaine 10 mg x ml(-1) in patients undergoing ...

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