conclusions office workers with chronic hepatitis c, treated with pegylated-interferon-α2b plus ribavirin, had work performance loss. in subjects treated with acetyl-l-carnitine supplementation we observed increased daily activity and reduced presenteeism and fatigue. acetyl-l-carnitinegroup had a smaller reduction of productivity comparing to placebo group. results significant difference were ...

Accurate assessment of mental fatigue level would improve operational safety and efficacy of astronauts for long-term space flight. Identification of neurophysiological markers can index impending overload or fatigue before performance decrements using neuroimaging technologies. The current study utilized functional near-infrared spectroscopy (fNIR) to investigate the relationship of hemodynami...

Severe fatigue can negatively affect quality of life, and oxidative stress may play a role in its mechanism. The aim of this study was to evaluate the effect of dietary supplementation of astaxanthin and sesamin (AS), strong food-derived antioxidants, on fatigue. Twenty-four healthy volunteers were supplemented with AS and placebo, each for four weeks. After each supplementation period, partici...

Objective: After traumatic brain injury (TBI) or stroke, long-term mental fatigue may occur with significant impact on work and social interactions. With the intention to measure mental fatigue irrespective of neurological illness, we developed the Mental Fatigue Scale (MFS). The scale incorporates affective, cognitive and sensory symptoms, duration of sleep and daytime variation in symptom sev...

PURPOSE The aim of this study was to test the hypotheses that prolonged mental exertion (i) reduces maximal muscle activation and (ii) increases the extent of central fatigue induced by subsequent endurance exercise. METHODS The neuromuscular function of the knee extensor muscles was assessed in 10 male subjects in two different conditions: (i) before and after prolonged mental exertion leadi...

Physical fatigue is a painful phenomenon which is localised in overstressed muscles. Mental fatigue is a diffuse sensation of weariness; it is a functional state, one of several intermediate conditions between the two extremes of alarm and sleep. A neurophysiological model of fatigue, involving an activating and inhibitory system has been developed. Fatigue in industrial practice has clinical s...

Mental fatigue is often characterized by reduced motivation for effortful activity and impaired task performance. We used subjective, behavioral (performance), and psychophysiological (P3, pupil diameter) measures during an n-back task to investigate the link between mental fatigue and task disengagement. After 2 h, we manipulated the rewards to examine a possible reengagement effect. Analyses ...

AIMS To study associations between characteristics of employees active at work and making a fatigue related visit to the general practitioner (GP) or occupational physician (OP) in terms of fatigue, physical health problems, mental health problems, psychosocial work characteristics, and attributions of their fatigue complaints. METHODS Self report questionnaires from the Maastricht Cohort Stu...

Mental fatigue is often characterized by reduced motivation for effortful activity and impaired task performance. We used subjective, behavioral (performance), and psychophysiological (P3, pupil diameter) measures during an n-back task to investigate the link between mental fatigue and task disengagement. After two hours we manipulated the rewards to examine a possible reengagement effect. Anal...