Maurice Gross (1934-2001) was both a great linguist and a pioneer in natural language processing. This article is written in homage to his memory. Maurice Gross is remembered as a vital man surrounded by a lively group, constituted by his laboratory, the LADL, and by his international network, RELEX. He and his group always resolutely steered away from any kind of abstemiousness or abstinence. ...

Monto Ho, a leader in the field of infectious diseases during the past 50 years and world-renowned expert in interferon and human herpesvirus infections of immunocompromised hosts, died 16 December 2013, after complications from a fall. Monto had the special ability to adopt the best qualities of Chinese and Western cultures to his everyday life and profession. Born in Yiyang, Hunan, China, in ...

arlo Lovisolo passed away on July 10th this summer after a prolonged battle with a glioblastoma. Born in Acqui Terme in October 1961, he was an outstanding physician and surgeon who enlightened his colleagues in ophthalmology with his surgical talent and meticulous observations, particularly in refractive surgery and most specifically in the field of phakic intraocular lens implantation. Carlo ...

Caltech neuroscientist Paul Patterson, whose career spanned developmental neurobiology, behavioral neuroscience, and neuroimmunology, passed away on June 25 at the age of 70 from an aggressive brain tumor. Patterson was a pioneer and an iconoclast who was not afraid to work outside of the scientific mainstream; consequently, he made a number of important and seminal contributions that opened up...

Articles Exascale Challenges for Optimization Andreas Grothey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Mathematical Optimization for Packing Problems Fernando M. de Oliveira Filho and Frank Vallentin . . . . 5 In Memoriam Che-Lin Su Richard W. Cottle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Bulletin Event Announcements SIAM Co...

Two-particle correlation functions are calculated for bosons emitted from a localized thermal source (the “glow” of a “hot spot”). In contrast to existing work, non-equilibrium effects up to first order in gradients of the particle distribution function are taken into account. The spectral width of the bosons is shown to be an important quantity: If it is too small, they do not equilibrate loca...

What’s Inside: Non-Point Sources 2 International Developments 2 2000 Moot Results 3 A River Does Run Through It! 4 Biosafety Accord in Montreal 5 Efficient Energy Alternatives 12 Chinese Scholar on CITES 13 Nuclear Letter to Pataki 15 Signatories to the Letter 16 Litigation Clinic Docket 17 In Memoriam: Dr. Kolbasov 27 In Print 28 On the Net 28 Vieques, Page 5 Aquaculture Law: Pollution or Promise

FEATURE – Dr. Jason Gotlib discusses the road to approval of midostaurin. MINI REVIEW – Drs. Luke Maese and Joshua Schiffman discuss recommendations for childhood cancer predisposition syndromes. ASK THE HEMATOLOGIST – Dr. Paul Moss covers practical issues to consider for CAR-T cell therapy. IN MEMORIAM – Dr. Alan Rosmarin pays tribute to the life of Dr. H. Jean Khoury (1967-2017). 5 4 15 12 AS...

Article Evolution of randomness in optimization methods for supervised machine learning Katya Scheinberg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 In Memoriam Jonathan Borwein Adrian Lewis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8 Roger Fletcher Sven Leyffer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....