نتایج جستجو برای: membrane stabilizing

تعداد نتایج: 409810  

2014
Siyuan Zhao Huanhuan Liao Meiying Ao Li Wu Xiaojun Zhang Yong Chen

While most attention has been focused on physiologically generated blebs, the molecular mechanisms for fixation-induced cell blebbing are less investigated. We show that protein-fixing (e.g. aldehydes and picric acid) but not lipid-stabilizing (e.g. OsO4 and KMnO4) fixatives induce blebbing on spread cells. We also show that aldehyde fixation may induce the loss or delocalization of phosphatidy...

2010
N. SAMPATH KUMAR

This study reports the human red blood cells (HRBC) and sheep red blood cells (SRBC) membrane stabilizing property and the antioxidizing property of ethyl acetate soluble fraction of the gynaceum part of Bombax ceiba. The probable mode by which Bombax ceiba mediates its effects on inflammatory conditions was studied on HRBC & SRBC exposed to hypotonic solution. The results of the study revealed...

Journal: :The Journal of pharmacology and experimental therapeutics 2005
Odile Sergent Manuella Pereira Corinne Belhomme Martine Chevanne Laurence Huc Dominique Lagadic-Gossmann

The relationship between bulk membrane fluidizing effect of ethanol and its toxicity due to oxidative stress is still unknown. To elucidate this issue, membrane fluidity of primary rat hepatocytes was studied by measuring order parameter after inhibition of ethanol-induced oxidative stress. We showed that pretreating cells with either 4-methyl-pyrazole (to inhibit ethanol metabolism), thiourea ...

Journal: :Blood 1990
P Jarolim M Lahav S C Liu J Palek

Oxidative injury to hemoglobin (Hb) leads to formation of methemoglobin (MetHb), reversible hemichromes (rHCRs), and irreversible hemichromes (iHCRs). iHCRs precipitate and form Heinz bodies that attach to the red cell membrane causing injury that leads to hemolysis. The molecular mechanisms of this membrane damage have not been fully elucidated. We have studied the effect of Hb oxidation produ...

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