نتایج جستجو برای: membrane form of adhesion molecules
تعداد نتایج: 21223220 فیلتر نتایج به سال:
Junctional adhesion molecule-A (JAM-A) serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). The membrane-distal immunoglobulin-like D1 domain of JAM-A is required for homodimerization and binding to reovirus attachment protein sigma1. We employed a structure-guided mutational analysis of the JAM-A dimer interface to identify determinants of reovirus binding. We ...
this work is presented in five parts. in the first part preparation of the starting complex [pt(c^n)cl(dmso)], 1, in which c^n = n(1),c(2?)-chelated, deprotonated 2-phenylpyridine, and dmso = dimethylsulfoxide, and its reaction with 1 equiv of the biphosphine ligands bis(diphenylphosphino)amine, dppa, or bis(diphenylphosphino)methane, dppm, to give the complex [pt(c^n)cl(dppa)], 2, or [pt(c^n)c...
– A phenomenological model for the unbinding transition of multi-component fluid membranes is proposed, where the unbinding transition is described using a theory analogous to Flory-Huggins theory for polymers. The coupling between the lateral phase separation of inclusion molecules and the membrane-substrate distance explains the phase coexistence between two unbound phases as observed in rece...
The formation of stable cell contacts is of pivotal importance for every metazoan life form. It is therefore not surprising that adhesive molecules appeared early during the evolution of multicellular organisms. The pioneering work of Johannes Holtfreter and others indicated that adhesive molecules, which reside in the plasma membrane on the surface of most cells, are not only important for est...
here, we report analysis of in vitro and in vivo drug release from an in situ formulation consisting of triamcinolone acetonide (tr) and poly(d,l-lactide-co-glycolide) (plga) and the additives glycofurol and hydroxyapatite nanoparticles (ha). we found that these additives enhanced drug release rate. we used the taguchi method to predict optimum formulation variables to minimise the initial burs...
Fertilization involves cell-cell fusion of a sperm with the oocyte. This fusion restores the diploid genome, activates the oocyte, and initiates embryonic development. The identification of proteins mediating the fusion of sperm with oocyte plasma membrane (oolemma) is important to a deeper knowledge of fertilization. Defects in sperm-oocyte fusion may account for some form of human infertility...
The neural cell adhesion molecule (NCAM) plays an important role in nervous system development. NCAM forms a complex between its terminal domains Ig1 and Ig2. When NCAM of cell A and of cell B connect to each other through complexes Ig12(A)/Ig12(B), the relative mobility of cells A and B and membrane tension exerts a force on the Ig12(A)/Ig12(B) complex. In this study, we investigated the respo...
Single letter and linear acuity (near and distance) and contrast sensitivity were measured in 15 amblyopes (ages 5 to 12) before, during, and after four weekly 7 min sessions of CAM treatment. Six of the children, however, played games over a homogeneous grey disc having the same space-averaged luminance as that of the striped stimuli. Experimental and controls results were indistinguishable. I...
Abstract Adhesion of T cells to antigen presenting is mediated by the TCR–MHCp and LFA1–ICAM1 protein complexes. These intercellular complexes segregate form characteristic special patterns in cell contact zone. Previous studies have attempted explain mechanisms formation these patterns. While emphasis has been put on membrane elasticity active cytoskeletal transport, it remains unclear whether...
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