نتایج جستجو برای: mef

تعداد نتایج: 1416  

2010
Jae-Mok Lee Towia A. Libermann Je-Yoel Cho

PURPOSE Bone tissues for clinical application can be improved by studies on osteoblast differentiation. Runx2 is known to be an important transcription factor for osteoblast differentiation. However, bone morphogenetic protein (BMP)-2 treatment to stimulate Runx2 is not sufficient to acquire enough bone formation in osteoblasts. Therefore, it is necessary to find other regulatory factors which ...

2015
Wen-ping Zhou Hui Zhang Yu-xia Zhao Gang-qiong Liu Jin-ying Zhang

OBJECTIVE Myocyte enhancer factor-2A (MEF 2A) has been shown to be involved in atherosclerotic lesion development, but its role in preexisting lesions is still unclear. In the present study we aim to assess the role of MEF 2A in the progression of pre-existing atherosclerosis. METHODS Eighty apolipoprotein E-deficient mice (APOE KO) were randomly allocated to control, scramble and MEF 2A RNA ...

2009
Yongxia Zhang Anatoliy Dragan Chris D. Geddes

In this paper, metal-enhanced fluorescence (MEF) from 6-propionyl-2-dimethylaminonaphthalene (Prodan) in different solvents when placed in close proximity to silver island films (SIFs), surface-deposited nanoparticles, is studied. We observe that MEF is wavelength dependent: the enhanced emission of Prodan on SIFs in different solvents changes from 1.5to 3-fold as compared to a glass control sa...

Journal: :Biotechnology progress 2008
Laleh Loghavi Sudhir K Sastry Ahmed E Yousef

Moderate electric fields (MEF) have been previously shown to alter the metabolic activity of microbial cells; thus, the effect of frequency and electric field would be of considerable interest. We investigated herein the effects of MEF frequency on microbial growth kinetics and bacteriocin (Lacidin A) production of Lactobacillus acidophilus OSU 133 during fermentation. The following fermentatio...

Journal: :The Journal of general virology 1982
G B Harnett G R Shellam

The in vitro growth of murine cytomegalovirus (MCMV) in mouse embryo fibroblasts (MEF) from Balb/c, C57BL, C3H and CBA mouse strains has been shown to correlate with the genetically determined in vivo susceptibility of these strains to MCMV infection. MEF from Balb/c and C57BL mice were more susceptible to MCMV than those from C3H and CBA mice. This was evident regardless of whether replication...

Journal: :Memorias do Instituto Oswaldo Cruz 2011
Naglaa Mohamed el-Lakkany Sayed Hassan Seif el-Din Abdel-Nasser Abdel-Aal Sabra Olfat Ali Hammam

Praziquantel (PZQ) is currently the only drug widely used for the treatment of schistosomiasis, but the antimalarial drug mefloquine (Mef) possesses interesting antischistosomal properties. Combination therapy with these two drugs has been suggested as a strategy for transmission control, as PZQ is active against adult worms and Mef is active against schistosomula. To examine the efficacy of co...

Journal: :Cell stem cell 2012
Elena Bazzoli Teodoro Pulvirenti Moritz C Oberstadt Fabiana Perna Boyoung Wee Nikolaus Schultz Jason T Huse Elena I Fomchenko Francesca Voza Viviane Tabar Cameron W Brennan Lisa M DeAngelis Stephen D Nimer Eric C Holland Massimo Squatrito

High-grade gliomas are aggressive and uniformly fatal tumors, composed of a heterogeneous population of cells that include many with stem-cell-like properties. The acquisition of stem-like traits might contribute to glioma initiation, growth, and recurrence. Here we investigated the role of the transcription factor myeloid Elf-1 like factor (MEF, also known as ELF4) in gliomas. We found that ME...

2017
S Warrier M Van der Jeught G Duggal L Tilleman E Sutherland J Taelman M Popovic S Lierman S Chuva De Sousa Lopes A Van Soom L Peelman F Van Nieuwerburgh D I M De Coninck B Menten P Mestdagh J Van de Sompele D Deforce P De Sutter B Heindryckx

Until recently, human embryonic stem cells (hESCs) were shown to exist in a state of primed pluripotency, while mouse embryonic stem cells (mESCs) display a naive or primed pluripotent state. Here we show the rapid conversion of in-house-derived primed hESCs on mouse embryonic feeder layer (MEF) to a naive state within 5-6 days in naive conversion media (NCM-MEF), 6-10 days in naive human stem ...

Journal: :Information Fusion 2021

Multi-exposure image fusion (MEF) is an important area in computer vision and has attracted increasing interests recent years. Apart from conventional algorithms, deep learning techniques have also been applied to MEF. However, although many efforts made on developing MEF the lack of benchmarking studies makes it difficult perform fair comprehensive performance comparison among thus hindering d...

Journal: :Biochemical and biophysical research communications 2011
Gerold Diez Vera Auernheimer Ben Fabry Wolfgang H Goldmann

This study evaluates the influence of vinculin in closed conformation on the mechanical properties of cells. We demonstrate that MEFvin(-/-) cells transfected with the eGFP-vinculin mutant A50I (talin-binding-deficient-vinculin in a constitutively closed conformation) show 2-fold lower stiffness and focal adhesion density compared to MEFvin(+/+) and MEF(Rescue) cells. MEF(A50I) cells are as sti...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید