The group I members of the Nm23 (non-metastatic) gene family encode nucleoside diphosphate kinases (NDPKs) that have been implicated in the regulation of cell migration, proliferation and differentiation. Despite their developmental and medical significance, the molecular functions of these NDPKs remain ill defined. To minimize confounding effects of functional compensation between closely rela...

Major complications associated with cardiac surgery are still common and carry great prognostic significance. β-Blockers, statins, antiplatelets, and renin-angiotensin system (RAS) blockers are current medical interventions to prevent cardiovascular complications in cardiac surgery. Renin-angiotensin system blockers include angiotensin-converting enzyme inhibitors, angiotensin II receptor block...

The aims of this study are to raise awareness among paediatricians, neurologists and paediatric neurologists of the potential benefits of permanent cardiac pacing in patients who have severe and disabling reflex anoxic seizures (RAS) associated with reflex asystole, sometimes called ‘pallid syncope’. Up to now pacing was generally held not to be required for RAS as it is self-limiting and safe....

recurrent aphthous stomatitis (ras) is known as the most common chronic disease of the oral cavity, which affects a range of 5-25% of the population. ras appears to be associated with some human leukocyte antigen (hla) class ii alleles and haplotypes. this study attempts to survey the distribution of hla-drb and -dqb alleles among iranian ras patients and healthy controls. in order to evaluate ...

BACKGROUND Colorectal cancer is frequent in the developed countries, with a cancer-specific mortality rate of 33%. Different biomarkers are associated with overall survival and the prediction of monoclonal treatment effectiveness. The presence of mutations in the K-ras oncogene alters the response to target therapy with cetuximab and could be an independent prognostic factor. AIMS To analyze ...

To investigate the K-ras genetic mutation status in colorectal cancer patients, compare the difference of K-ras genetic mutation rate in Han and Uygur nationality and analyze the influencing factor. 91 cases (52 cases of Han nationality and 39 cases of Uygur nationality) of colorectal biopsy or surgical ablation pathology specimen from the first affiliated hospital of Xinjiang Medical Universit...

OBJECTIVE To assess the frequency of adverse drug event (ADE)-related admissions (ADE-RAs) during a prospective medical record review of patients admitted to a metropolitan tertiary referral hospital. METHODS Potential ADE-RA cases were identified by examination of case records of randomly selected patients. Cases were assessed by an expert panel to measure study outcomes, which were the freq...

OBJECTIVE To find out the relationship between recurrent aphthous stomatitis (RAS) with deficiencies of haemoglobin, haematocrit, serum vitamin B12, serum Ferritin and red blood cells (RBC) Folate level. STUDY DESIGN An analytical cross-sectional study. PLACE AND DURATION OF STUDY Department of Oral Health Sciences, Shaikh Zayed Federal Postgraduate Medical Complex, Lahore, from February to...

The aims of this study are to raise awareness among paediatricians, neurologists and paediatric neurologists of the potential benefits of permanent cardiac pacing in patients who have severe and disabling reflex anoxic seizures (RAS) associated with reflex asystole, sometimes called ‘pallid syncope’. Up to now pacing was generally held not to be required for RAS as it is self-limiting and safe....

Article history: Received: 25 Feb 2012 Accepted: 12 May 2012 Available online: 7 Jan 2013 ZJRMS 2014; 16(1): 36-39 Background: Kidney transplantation is the best treatment option for kidney failure. Major medical progress has been made in the field of renal transplantation over the last 40 years. The surgical procedure has been standardized and the complication rate is low. Overall, the outcome...