Members of the multidrug resistance protein (MRP/ABCC) subfamily of ATP-binding cassette proteins transport a wide array of anionic compounds, including sulfate, glucuronide, and glutathione (GSH) conjugates. The present study tested the ATP-dependent vesicular transport of leukotriene C(4) and 17beta-estradiol 17-(beta-d-glucuronide) (E(2)17betaG) mediated by the MRP1 and MRP2 transporters in ...

Biochips, a novel technology in the field of biomolecular analysis, offer promising alternative to conventional testing equipment. These chips integrate multiple functions within single system, providing compact and efficient solution for various needs. For biochips, pattern-control micro-electrode-dot-array (MEDA) is new, universally viable design that can replace microchannels other micro-com...

In this paper, a method for building data dictionaries (DDs) is discussed, which can be used to support query processing in feder-ated systems. In this method, the meda data stored in a DD are organized into three classes: structure mappings, concept mappings and data mappings. Based on them, a query submitted to a federated system can be decomposed and translated, and the local results can be ...

Abstract To solve dynamic multi-objective optimization problems better, the key is to adapt quickly environmental changes and track possible changing optimal solutions in time. In this paper, we propose a special point-based transfer component analysis for algorithm (SPTr-RM-MEDA). be specific, when change occurs, neighbors of some points are selected from set at previous time, makes use minimi...

The Finnish Meteorological Institute (FMI) provides a relative humidity measurement sensor (HS) for NASA's Mars 2020 rover. is part of the Environmental Dynamic Analyzer (MEDA), suite environmental sensors provided by Spain's Centro de Astrobiología. main scientific goal to measure Martian atmosphere near surface and complement previous mission atmospheric measurements better understanding cond...

In this paper we consider a complete connected noncompact Riemannian manifold M with Ricci curvature bounded from below, positive injectivity radius and spectral gap b. We introduce a sequence X(M), X(M), . . . of new Hardy spaces on M , the sequence Y (M), Y (M), . . . of their dual spaces, and show that these spaces may be used to obtain endpoint estimates for spectral multipliers associated ...

The filamentous fungus Fusarium oxysporum is a soil-borne facultative parasite that causes economically important losses in a wide variety of crops. F. oxysporum exhibits filamentous growth on agar media and undergoes asexual development producing three kinds of spores: microconidia, macroconidia, and chlamydospores. Ellipsoidal microconidia and falcate macroconidia are formed from phialides by...

Aldo Rossi was obsessed with the schéma of cube, according to Lobsinger (2002), from Resistance Monument in Cuneo (1962, collaborated Gianugo Polesello and Luca Meda), via Modena Cemetery (New San Catardo Modena, 1971-1980s), Teatre del Monde (1979-1980).