Endocytic vesicle formation is a complex process that couples sequential protein recruitment and lipid modifications with dramatic shape transformations of the plasma membrane. Although individual molecular players have been studied intensively, how they all fit into a coherent picture of endocytosis remains unclear. That is, how the proper temporal and spatial coordination of endocytic events ...

A theory of molecular motors is presented that explains how the energy released in single chemical reactions can generate mechanical motion and force. In the simplest case the fluctuating movements of a motor enzyme are well described by a diffusion process on a two-dimensional potential energy surface, where one dimension is a chemical reaction coordinate and the other is the spatial displacem...

Two phenomena will be considered. Phase transformations (PTs) and chemical reactions (CRs) under compression and shear of materials in rotational diamond anvil cell (RDAC) represent examples of apparent effects of plastic shear. We recently predicted the new phenomenon that crystal-crystal and crystalamorphous PTs can occur through virtual melting (VM) significantly below (> 1000K!) the melting...

Mechanochemistry has attracted a lot of attention over the last few decades with rapid growth in number publications due to its unique features. However, very little is known about how mechanical energy converted into chemical energy. Most published works using mechanochemistry neglect required experimental parameters and their effect resulting products, what makes extremely difficult reproduce...