We investigated the use of mechanical stress to bend carbon-carbon triple bonds. Formation of an isoquinoline after reaction with a benzyl azide trap points towards a nucleophilic addition mechanism, differentiating mechanochemical trans-bending of π bonds from the typical reactivity observed for cisoidal bending of triple bonds in strained cyclic alkynes.

Environmentally friendly one-pot synthesis of amides, bis-amides and dipeptides by mechanochemical carbodiimide-mediated coupling of carboxylic acids and amines is described; high reaction yields and simple aqueous work-up allow for the clean, practical and fast preparation of a variety of compounds containing the amide bond from readily accessible reagents.

We describe the nearly quantitative preparation of phosphorus ylides and the Wittig reaction occurring in the solid sate during high-energy mechanochemical processing. Initial insights into the details of the discovered chemical transformations indicate that high-energy mechanical processing supports the interaction of reacting centers by breaking crystallinity of the reactants and by providing...

Self-organization in cells often manifests itself in oscillations and waves. Here, we address deformation waves in protoplasmic droplets of the plasmodial slime mold Physarum polycephalum by modelling and experiments. In particular, we extend a one-dimensional model that considered the cell as an poroelastic medium, where active tension caused mechanochemical waves that were regulated by an inh...

in this article vanadium boride nanopowder was synthesized by mechanochemical reduction method in a high-energy ball mill. the synthesized powders were studied by x-ray diffraction (xrd), scanning electron microscopy (sem), xray map and transmission electron microscopy (tem). according to x-ray diffraction the product predominantly consists of vb phases after 100 min milling without further hea...