aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (pcl), poly (vinyl alcohol) (pva) and hydroxyapatite nanoparticles (nha). the morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...

The development of a prototypc Compton scaltering camera based on two 1 cm3 cubic 3-D position scnsitivc CZT detectors is iindcrway in our laboratory. As a practical problem, the mechanical alignmcnt error may be larger than the 1 mm detector position rcsolution. This paper investigates thc cffccts of any possible mechanical alignmcnt error on the reconstructed images by Montc Carlo simulations...

BACKGROUND Single photon emission computerized tomography and conventional computerized tomography (SPECT/CT) tracer uptake has been shown to reflect the loading history of the tibiofemoral knee joint and correlate with the mechanical and anatomical alignment. It was our primary purpose to develop a novel standardized SPECT/CT algorithm for patients undergoing high tibial osteotomy, evaluate th...

the provision of an adequate quantity of cells with proper function and purity is one of the main challenges of tissue engineering studies. stem cells, with their self-renewal and differentiation capacity, are considered one of the main cell sources in the field of tissue engineering. previously, the use of chemical factors seemed to be the only possible way for stem cell differentiation. howev...

INTRODUCTION The use of robotics in total knee arthroplasty (TKA) has been shown to minimise human error, as well as improve the accuracy and precision of component implantation and mechanical axis alignment. The present study aimed to demonstrate that robot-assisted TKA using ROBODOC® is safe and capable of producing a consistent and accurate postoperative mechanical axis. METHODS We prospec...

OBJECTIVES The purpose of this study was to compare the intra-operative benefits and the clinical outcomes from kinematic or mechanical alignment for total knee arthroplasty (TKA) in patients undergoing revision of failed unicompartmental kneel arthroplasty (UKA) to TKA. METHODS Ten revisions were performed with a kinematic alignment technique and 11 with a mechanical alignment. Measurements ...

Recent studies have challenged the long-held notion that neutral mechanical alignment after total knee arthroplasty leads to optimal function and survivorship.The ideal alignment for function and survivorship may actually be different.Kinematic alignment, where components are implanted to re-create the natural flexion/extension axis of the knee, may lead to improved functional results.Residual ...

One of the most common modes of failure for total knee arthroplasty is aeseptic loosening of the components [2]. Aeseptic loosening failure of both the femoral and tibial components has been shown to occur if the alignment of the knee occurs outside of ± 3° from the mechanical alignment in the coronal plane [3]. Proper mechanical alignment of the knee is dependent on the correct proximal varus/...

Correct positioning and alignment of components during primary total knee replacement (TKR) is widely accepted to be an important predictor of patient satisfaction and implant durability. This retrospective study reports the effect of the post-operative mechanical axis of the lower limb in the coronal plane on implant survival following primary TKR. A total of 501 TKRs in 396 patients were divi...

background: mesenchymal stem cells (mscs) can be expanded and differentiated into many mature cell types including smooth muscle cells (smcs). in addition to growth factor, cyclic stretch contributes to differentiation of stem cells. mechanical stimuli are critical to morphological changes, development, regeneration, differentiation and pathology of mesenchymal tissues. the aim of this study is...