BACKGROUND We examined the effect of adult weight change on risk for total hip replacement resulting from primary osteoarthritis, using a prospective study design. METHODS We linked data on body mass index and body weight from 3 screening surveys in 3 Norwegian counties (mean ages at screenings 34, 43, and 47 y; n = 38,868) with follow-up data on total hip replacement (n = 572). Mean age at t...

OBJECTIVE To evaluate the quality of weight change (change in fat mass vs fat-free mass [FFM]), changes in cardiorespiratory fitness (CRF), and frequencies of metabolic risk factors in adolescent females with obesity who either lost or gained weight following lifestyle treatment. STUDY DESIGN Fifty-eight girls (mean age = 13.0 ± 1.6 years; 77% black; mean body mass index = 36.5 ± 4.5 kg/m(2))...

BACKGROUND Controversy exists regarding the optimal rate of weight loss for long-term weight management success. PURPOSE This study examined whether gradual initial weight loss was associated with greater long-term weight reduction than rapid initial loss. METHODS Groups were drawn from participants in the TOURS trial, which included a sample of middle-aged (mean = 59.3 years) obese women (...

BACKGROUND Obesity, which is epidemic in the United States, is associated with increased morbidity and mortality. The combination of diet, exercise, and a behavior-modification program often does not result in ideal body weight. OBJECTIVE The aim of this study was to determine the efficacy of phentermine (Phen) alone compared with phentermine plus fenfluramine (Phen-Fen), when used in combina...

OBJECTIVE To summarise the effects of anthelmintic drug treatment on growth and cognitive performance in children. DATA SOURCES Electronic databases: Cochrane Infectious Diseases Group controlled trial register, Cochrane controlled trials register, Embase, and Medline. Citations of all identified trials. Contact with the World Health Organization and field researchers. REVIEW METHODS System...

Ten non pregnant, non lactating Corriedale ewes ate an average of 148 g fuzzy whole cotton seed per sheep per day and their mean weight fell from 40.3 to 32.2 kg over an eight week period. Two of the sheep died. A similar group of ewes, offered a mixture of 227 g of cottonseed and 227 g of wheat per sheep per day, usually ate all the ration. At the end of an 18 week period, there were no signif...

BACKGROUND The epidemiological evidence supporting a causal link between Mediterranean diets and body weight is contrasting. We evaluated the effect of Mediterranean diets on body weight in randomized controlled trials (RCTs) using a meta-analysis. METHODS We searched English and non-English publications in PubMed, Embase, Scopus, and the Cochrane Central Register of Controlled Trials from in...

IMPORTANCE Few weight loss treatments produce clinically meaningful weight loss outcomes among black women, particularly in the primary care setting. New weight management strategies are necessary for this population. Weight gain prevention might be an effective treatment option, with particular benefits for overweight and class 1 obese black women. OBJECTIVE To compare changes in weight and ...

BACKGROUND Gastric balloon therapy (GBT) is a temporary, nonsurgical treatment for obesity. This retrospective study evaluates safety and efficacy of GBT in obese patients. METHODS The BioEnterics. Intragastric Balloon (BIB) was endoscopically implanted into each patient's stomach and inflated with saline (450-750 ml). Extraction was planned after 6 months. Data from 190 patients receiving GB...

A systematic review, meta-analysis and meta-regression were conducted to evaluate the effectiveness of behavioural weight management programmes and examine how programme characteristics affect mean weight loss. Randomized controlled trials of multicomponent behavioural weight management programmes in overweight and obese adults were included. References were obtained through systematic searches...