نتایج جستجو برای: mdr tb
تعداد نتایج: 31722 فیلتر نتایج به سال:
Globally, the incidence of tuberculosis (TB) is declining but the proportion of drug-resistant cases has increased. Strains resistant to both isoniazid and rifampin, and possibly other antibiotics, called multidrug-resistant (MDR), are particularly difficult to treat. Poorer outcomes, including increased mortality, occur in patients infected with MDR strains and the costs associated with treatm...
BACKGROUND Multidrug resistant tuberculosis (MDR-TB), is an emerging public health problem in sub-Saharan Africa (SSA). This study aims to determine the trends in prevalence of MDR-TB among new TB cases in sub-Saharan Africa over two decades. METHODS We searched electronic data bases and accessed all prevalence studies of MDR-TB within SSA between 2007 and 2017. We determined pooled prevalenc...
Multidrug-resistant tuberculosis (MDR-TB; resistance to at least rifampicin and isoniazid) is a global public health concern. In 2010–2011, Uzbekistan, in central Asia, conducted its first countrywide survey to determine the prevalence of MDR-TB among TB patients. The proportion of MDR-TB among new and previously treated TB patients throughout the country was measured and risk factors for MDR-T...
study of kir expression and hla ligands in cd56+ lymphocytes of drug resistant tuberculosis patients
analysis of receptor–ligand interactions in the context of diseases necessitates to understand how hla–kir genotypes function in diseases. although cd56+ lymphocytes are derived from multiple lineages, they share a functional association with immunosurviellance and antimicrobial responses. the present study aimed to determine whether kir phenotype in cd56 lymphocytes and corresponding...
Objectives. Multi-drug resistant tuberculosis (MDR-TB) is a threat to TB control. To guide TB control, it is essential to understand the extent to which and the circumstances in which MDR-TB will replace drug-susceptible TB (DS-TB) as the dominant phenotype. We examined the issue by presenting evidence from genomics, pharmacokinetics and epidemiology studies. We then synthesised this evidence i...
BACKGROUND Rapid and effective diagnosis of multidrug-resistant tuberculosis (MDR-TB) is an essential component of global tuberculosis (TB) control, but most MDR-TB cases are still not diagnosed. OBJECTIVE To assess whether patient sputum bacterial load can be used to identify patients at increased risk of MDR-TB. METHODS We used a case-control study and multivariable logistic regression mo...
Background: Multi-drug resistant tuberculosis (MDR-TB) is a serious health problem with high morbidity and mortality. The identification of risk factors needed to prevent the incidence TB-MDR. Objective: To identify TB-MDR in Special Region Yogyakarta.Method: This study used case control design assess for MDR-TB. Patients diagnosed MDR-TB compared non-MDR TB patients were then exposure studied....
A study of multidrug-resistant tuberculosis in risk groups in the city of Santos, São Paulo, Brazil.
Monitoring the extent of and trends in multidrug-resistant tuberculosis (MDR-TB) is a priority of the Brazilian National Tuberculosis Control Programme. The current study aimed to estimate the incidence of MDR-TB, describe the profile of TB drug resistance in risk groups and examine whether screening for MDR-TB adhered to the recommended guidelines. A descriptive study that examined diagnosed c...
BACKGROUND Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) hinder the progress of TB control. OBJECTIVE To track the trend of drug-resistant tuberculosis (DR-TB) prevalence in Zhejiang Province from 1999 to 2013, and identify risk factors of resistance to second-line drugs among MDR-TB patients. DESIGN Four DR-TB surveys had been done in Zhejia...
BACKGROUND In South Africa, patients with multi-drug-resistant tuberculosis (MDR-TB) are hospitalised from MDR-TB treatment initiation until culture conversion. Although MDR-TB accounts for <3% of incident TB in South Africa, 55% of the public sector TB budget is spent on MDR-TB. To inform new strategies for MDR-TB management, we estimated the per-patient cost (USD 2011) of inpatient MDR-TB tre...
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