BACKGROUND AND PURPOSE The emergence of multidrug-resistant (MDR) Pseudomonas aeruginosa is a challenging clinical problem. This study investigated the source of an outbreak of MDR P. aeruginosa infections and the role of combination therapy in its management. METHODS MDR P. aeruginosa isolates were collected at the MacKay Memorial Hospital, Taipei, Taiwan, and antibiotic synergy was investig...

Abstract. Prastiyanto ME, Darmawati S, Mukaromah AH. 2022. In vitro evaluation of the antibacterial activity seed kernel extracts seven mangoes (Mangifera indica) cultivars native to Indonesia against MDR-Pseudomonas aeruginosa isolated from wounds. Biodiversitas 23: 5629-5637. Pseudomonas aeroginusa is most common bacterium causing wound infections, with solution being antibiotics. However, ex...

Globally, tuberculosis infections continue to increase their resistance to antibiotics. Multidrug resistant tuberculosis infections (MDR TB) have progressed to extensively drug resistance status (XDR TB) and the latter have evolved in some parts of the world to totally drug resistant (TDR TB) infections. MDR TB is difficult to treat successfully, and when therapy is ineffective, a single case c...

the emergence of multidrug resistance (mdr) and extensively drug resistance (xdr) in acinetobacter baumannii has made an important challenge in the treatment of infections caused by this organism. the ability of carbapenemase production is one of the main mechanisms for the emergence of mdr and/or xdr in a. baumannii. the aim of this study was to detect carbapenemase producer a. baumannii. in t...

Background: Multi drug resistance (MDR) P. aeruginosa consider the main cause of morbidity in hospitalize patients suffering from chronic airway infections such as pulmonary disease, pneumonia and cystic fibrosis (CF). Also, rapidly development antibiotic to last generations a broad spectrum were detected for many isolates. Accordingly vaccines have potential prevent treatment infections. Aim: ...

Continuous deployment of antifungals in treating infections caused by dimorphic opportunistic pathogen Candida albicans has led to the emergence of drug resistance resulting in cross-resistance to many unrelated drugs, a phenomenon termed as Multi-Drug Resistance (MDR). Although there is reasonable understanding of major factors which contribute to MDR mechanisms, it appears unavoidable to cons...

BACKGROUND Aiming to improve outcome of lung transplantation (LTx) patients, we reviewed risk factors and treatment practices for the LTx recipients who experienced respiratory infection in the late post-LTx period (>1 month after LTx). METHODS We analyzed the clinical data of 48 recipients and donors from 61 LTx, who experienced late respiratory infections. Late respiratory infections were c...

Background: Infections by multidrug-resistant (MDR) microorganisms are associated with increased morbidity and mortality in burn patients. This study aimed to analyze the evolution of MDR bacteria over a five-year period at Coimbra Burns Unit (CBU) Portugal, seeking assess possible associations specific presumed risk factors. Methods: The data obtained consisted identified present any microbiol...