Gorham's disease is a rare benign cause of progressive massive idiopathic osteolysis. The clinician's acute awareness and high degree of suspicion are required for diagnosis because of its rarity and variable clinical presentation. Distinctive radiological and histopathological features may help in this regard. Though eventual stabilisation of the affected bone is the most common sequel, sponta...

Gorham syndrome is a rare disease that presents as progressive osteolysis, and may affect any part of the skeleton. The pathologic process involves the replacement of normal bone by aggressively expanding but non-neoplastic vascular tissue, resulting in massive osteolysis of the adjacent bone. If the spine and ribs are affected, the subsequent kyphosis and chest wall deformity may cause severe ...

Gorham-Stout syndrome is a rare disorder that leads to extensive lymphangiomatosis in bones with resorption of adjacent bone matrix. As a result, the disease is also known as massive osteolysis or “vanishing bone disease.” Although the disease primarily occurs in bone, it may also involve adjacent soft tissues. We report a case of Gorham-Stout syndrome presented with chylotamponade as a result ...

Revision anterior cruciate ligament (ACL) reconstruction is substantially more challenging than primary reconstruction. Management of previously malpositioned or widened tunnels often requires innovative approaches for managing bony defects. Massive osteolysis with poor bone stock and convergence or overlapping of revision tunnels into the previously placed tunnels may necessitate a staged revi...

Gorham-Stout syndrome is a rare disorder that leads to extensive lymphangiomatosis in bones with resorption of adjacent bone matrix. As a result, the disease is also known as massive osteolysis or “vanishing bone disease.” Although the disease primarily occurs in bone, it may also involve adjacent soft tissues. We report a case of Gorham-Stout syndrome presented with chylotamponade as a result ...

Multiple variants of haemangiomas are reported, depending on variable histological features. Haemangioma: cavernous, capillary, epithelioid. Angiomatosis: non-aggressive (regional), dissemi-nated (cystic angiomatosis), aggressive (massive osteolysis). Clinics and pathology Disease Haemangioma. Phenotype / cell stem origin Endothelial cell. Etiology It is suggested that these lesions are congeni...

Seven cases of massive osteolysis are presented. The aetiology of this disease is as yet unknown; neither age nor sex seems to be a factor in its incidence, nor are standard bone grafts or radiotherapy successful methods of treatment. However, in this series, operation produced a satisfactory outcome for five patients at a mean follow-up of 17 years; in three of these patients a custom-built pr...