Iron overload is a clinical problem which can be prevented by using iron chelating agents. An alternative method of relieving iron overload is to reduce iron absorption from the intestine by administering specific iron chelating agents, which can bind iron to form nonabsorbable complexes. Based on this strategy, a series of polymeric ligands containing the chelating moiety 3-hydroxypyridin-4-on...

Introduction: Due to the cell labeling potentials of various metal-maltol complexes, the idea of developing a possible cell labeling imaging agent using single photon emission computed chromatography (SPECT) with [In]-maltolate complex has been investigated. Methods: [In] labeled 3-hydroxy-2-methyl-4H-pyran-4-onate ([In]-maltolate) was prepared using freshly prepared [In]InCl3 and 3-hydroxy-2-m...

The aim of this study is to evaluate the bioactive compounds in the ethanolic leaf extract of Azima tetracantha by using Gas chromatographyMass Spectrometry (GCMS). Azima tetracantha leaves were collected from Ariyalur District, Tamil Nadu. The dried leaf powder was extracted with the solvent ethanol by using Soxhlet apparatus. One microlitre of the extract was subjected for analysis by GCMS to...

The biochemical activity and morphology of control and streptozotocin-diabetic rat liver Golgi complexes were previously investigated by us under influence of some vanadium [V(IV)] compounds. The effectiveness of these derivatives depends on the kind of complexing ligands. This paper presents the investigation of the effect of bipyridyl, the ligand of a new vanadium compound, tested by us with ...

Ternary complexes of copper(II) and zinc(II) metal ions with the ligands maltol; 3-hydroxy-2-methyl-4H-pyrone (MA) and glycylglycine (GG) have been synthesized and characterized by IR, H NMR, UV-Visible, mass spectra and TGA techniques. The complexes have been screened for antibacterial activity and the results are compared with the activity of free ligands. Increased activity of ternary comple...

The reaction of the dimer [Rh(III)(pentamethylcyclopentadienyl)(μ-Cl)Cl]2 ([Rh(III)(Cp*)(μ-Cl)Cl]2) with the hydroxypyrone ligands maltol and allomaltol affords complexes of the general formula [Rh(III)(Cp*)(L)Cl] under standard and microwave conditions. The organometallic compounds were characterized by standard analytical methods and in the case of the allomaltol derivative in the solid state...

The understanding of the biotransformations of insulin mimetic vanadium complexes in human blood and its transport to target cells is an essential issue in the development of more effective drugs. We present the study of the interaction of oxovanadium(iv) with human serum albumin (HSA) by electron paramagnetic resonance (EPR), circular dichroism (CD) and visible absorption spectroscopy. Metal c...