BACKGROUND Tetanus is a life threatening disease. Reported mortality for tetanus is 15-39%. Conventional treatment includes heavy sedation and artificial ventilation. Complications resulting from long term heavy sedation and artificial ventilation contribute to 60% of the total mortality caused by tetanus. In this study magnesium sulphate was used to reduce the need for sedation and artificial ...

BACKGROUND Magnesium sulphate is extensively used in obstetrics for the treatment and prevention of eclampsia. A recent meta-analysis has shown that magnesium sulphate is an effective fetal neuroprotective agent when given antenatally to women at risk of very preterm birth. Term infants account for more than half of all cases of cerebral palsy, and the incidence has remained fairly constant. It...

BACKGROUND This prospective, randomized study was designed to compare remifentanil and magnesium sulphate during middle ear surgery in terms of postoperative pain and other complications. METHODS Eighty patients undergoing middle ear surgery were enrolled in the study. Patients were randomized into two groups of 40 to receive remifentanil (Group R) or magnesium sulphate (Group M) infusion. Pr...

The therapeutic index of magnesium is said to be low, hence, there are fears of toxicity when used as anticonvulsant in eclamptic patients. The objective of this study was to determine the serum levels of magnesium in eclamptic patients treated with magnesium sulphate and relate the levels with clinical indicators. It was a prospective study involving consecutive eclamptic patients that were ma...

BACKGROUND Magnesium sulphate is currently recommended for neuroprotection of preterm infants for women at risk of preterm birth at less than 30 weeks' gestation, based on high quality evidence of benefit. However there remains uncertainty as to whether these benefits apply at higher gestational ages.The aim of this randomised controlled trial is to assess whether giving magnesium sulphate comp...

The development of symptomless cyanosis followed the administration of drugs of the sulphonamide groups. The simultaneous administration of magnesium sulphate is to be noted as a probable etiological factor. Colebrook', in his first series of forty cases, all of whlIoim were taking magnesium sulphate, had three cases of sulph<moglobinaemia. In his second series2 of twxenty-six cases similarly t...

BACKGROUND The aim of this study was to assess the cost-effectiveness of administering magnesium sulphate to patients in whom preterm birth at < 32+0 weeks gestation is either imminent or threatened for the purpose of fetal neuroprotection. METHODS Multiple decision tree models and probabilistic sensitivity analyses were used to compare the administration of magnesium sulphate with the altern...

Magnesium chloride, though cost wise roughly same as of ferrous sulphate, is less commonly used coagulant in comparison to the ferrous sulphate for the treatment of wastewater. The present study was conducted to investigate the comparative effectiveness of ferrous sulphate (FeSO4.7H2O) as iron based salt and magnesium chloride (MgCl2) as magnesium based salt in terms of decolorization and chemi...

BACKGROUND Magnesium is well known to inhibit catecholamine release and attenuate vasopressin-stimulated vasoconstriction. We investigated whether i.v. magnesium sulphate attenuates the haemodynamic stress responses to pneumoperitoneum by changing neurohumoral responses during laparoscopic cholecystectomy. METHODS Thirty-two patients undergoing laparoscopic cholecystectomy were randomly assig...

Introduction: This randomized, double-blind, prospective study was undertaken to evaluate the effect of magnesium sulphate in attenuating the stress responses associated with laparoscopic abdominal surgeries. Methods: 62 patients who underwent laparoscopic abdominal surgery were randomly divided in to two groups, group I and group II. 5 minutes after intubation but before creation of pneumoperi...