PURPOSE To compare the effect of conventional and femtosecond laser-assisted (Alcon LenSx Inc) phacoemulsification on the macula using optical coherence tomography (OCT). METHODS Twenty eyes of 20 patients underwent uneventful cataract surgery in both study groups: femtosecond laser-assisted (laser group) and conventional phacoemulsification (control group). Macular thickness and volume were ...

AIMS To estimate disease progression based on analysis of macular volume measured by spectral-domain optical coherence tomography (SD-OCT) in patients affected by Stargardt macular dystrophy (STGD1) and to evaluate the influence of software errors on these measurements. METHODS 58 eyes of 29 STGD1 patients were included. Numbers and types of algorithm errors were recorded and manually correct...

BACKGROUND The purpose of this study was to investigate the visual and anatomic outcomes in patients with chronic macular edema who underwent 25-gauge pars plana vitrectomy with internal limiting membrane peeling. METHODS This study was a retrospective chart review of 24 eyes from 21 patients who underwent 25-gauge pars plana vitrectomy and indocyanine green-assisted internal limiting membran...

OBJECTIVE To collect a normative database of macular thickness, retinal nerve fiber layer (RNFL) thicknesses, and optic nerve topography in the healthy eyes of children aged 3 to 17 years using optical coherence tomography (OCT) measurements. METHODS Scans were obtained for 286 healthy children (black, 114; white, 154; other, 18). Each child had a dilated eye examination, an axial length meas...

PURPOSE The aim of the present study was to compare macular thickness in patients with keratoconus (KC) with macular thickness in healthy subjects. SUBJECTS AND METHODS Twenty-six patients with KC and 52 control subjects were included. The macular structure was evaluated using a Zeiss Cirrus HD-OCT. The scan pattern used was 512 × 128, which covers an area of approximately 6 × 6 mm of the ret...

purpose : to compare the 6-months anatomic and best corrected visual acuity (bcva) responses after primary intravitreal bevacizumab (ivb intravitreal avastin) and ivb plus macular photocoagulation (mpc) in diabetics with clinically significant macular edema (csme) methods : in this interventional randomized clinical trial (rct) 40 diabetics (80 eyes) with bilateral csme and non-proliferative di...

Bestrophins are a newly identified family of Cl(-) channels. Mutations in the founding member of the family, human bestrophin-1 (hBest1), are responsible for a form of early onset macular degeneration called Best vitelliform macular dystrophy. The link between dysfunction of hBest1 and macular degeneration remains unknown. Because retinal pigmented epithelium (RPE) cells may be subjected to var...

PURPOSE To show a case in which the shape of the fovea changed after an asymptomatic macular posterior vitreous detachment (PVD). METHODS The foveal shape was determined from the spectral-domain optical coherence tomography (OCT) images before and after a spontaneous macular PVD. RESULTS A 66-year-old man with a unilateral macular hole in the right eye presented with a perifoveal PVD in the...

BACKGROUND AND OBJECTIVE To determine whether the volumes of macular layers before and after epiretinal membrane (ERM) peeling as measured by spectral-domain optical coherence tomography (SD-OCT) correlated with best-corrected visual acuity (BCVA) or ERM location. PATIENTS AND METHODS Thirty-six eyes with idiopathic ERM and 12 control eyes were imaged preoperatively and postoperatively using ...

[This corrects the article on p. 357 in vol. 11, PMID: 27069359.].