Abstract Our objective was to evaluate effects of technological management strategies on environmental impacts and net returns feedlot operations in the United States. Feedlot were simulated with Integrated Farm System Model (IFSM 4.6; USDA-ARS, University Park, PA) quantify baseline production full US beef cattle systems. Strategies included: ionophore, implant, ractopamine hydrochloride, comb...

Novel and effective calcium ion binding molecular fluorescent probes have been developed by systematic structural modification of BAPTA ionophore. The comprehensive computational studies suggested the role coordination number in chelator moiety.

P-glycoprotein, encoded by the multidrug resistance gene MDR1, is an ATP-driven drug efflux pump which is highly expressed at the blood-brain barrier of vertebrates. Drug efflux of macrocyclic lactones by P-glycoprotein is highly relevant for the therapeutic safety of macrocyclic lactones, as thereby GABA-gated chloride channels, which are confined to the central nervous system in vertebrates, ...

We report the draft whole-genome sequence of Rothia nasimurium isolated from a porcine tonsil. The genome encodes a nonribosomal peptide synthetase predicted to produce valinomycin, a cyclic dodecadepsipeptide ionophore. Previously, valinomycin was known to be produced only by Streptomyces species and isolates belonging to the Bacillus pumilus group.

Reaction between 4-aminopyridine and a dinuclear zinc(II) component of a Robson macrocyclic ligand has resulted in the formation of a molecular ladder element motif. X-ray single crystal structural analysis indicates that two pyridine rings are assembled at the same direction of the macrocycle, which are placed in a nearly parallel way via pi-pi interactions, forming a concavity structure with ...

Synthetic amphiphiles have been found to self-assemble into a variety of structures such as micelles, vesicles, cylinders and lamellae in aqueous media over many length scales. We report herein cation-induced aggregation of hexaaza-cyclophanes in water. Pd(2+)- or proton-induced formation of submicro spherical aggregates was observed by several spectroscopic and microscopic methods.

Applying spectroelectrochemistry to all-solid-state electrodes composed of poly(3-octylthiophene) (POT) and an ultrathin ion-selective membrane on top, it is possible monitor the dynamic charge transfer (CT) in POT when this event coupled ion transfers (ITs) promoted by absence/presence a selective ionophore membrane. Herein, we report combination empirical theoretical evidence revealing that d...

Using recognition moieties that bind to the inner co-ordination sphere of a monomeric DO3A-type di-aqua complex, dimeric poly(aminocarboxylate) gadolinium(III) compounds can be formed with greatly enhanced relaxivities, arising from optimized contributions of inner- and second spheres of hydration.