most current references recommend divided doses of prednisolone for the initial treatment of idiopathic minimal change nephrotic syndrome in children, with relapse occuring in the majority of them, but there is little experience concerning single-dose prednisolone therapy, especially considering the relapse rate. in this prospective study on 36 consecutive children with primary nephrotic syndro...

background: for adult all patients, the indications and appropriate timing of allogeneic hematopoietic stem cell transplantation (ahsct) continue to be debated. the primary aim of this single-institution study was to compare the results of our adult all patients that had been allografted with those reported in the current literature. subjects and methods: this study included 53 consecutive adul...

BACKGROUND The study was conducted to examine esophageal and gastric cardia precursor progression. METHODS After population-based baseline screening, 145 precursor and 335 chronic inflammation cases were endoscopically surveyed for six years. RESULTS Surveillance of interval and baseline diagnoses for 18 severe dysplasia (SD) cases later detected were: 13, 23, 39, and 44 months since a diag...

Auditory change detection is crucial for the development of the auditory system and a prerequisite for language development. In neonates, stimuli with broad spectral width like white noise (WN) elicit the highest response compared to pure tone and combined tone stimuli. In the current study we addressed for the first time the question how fetuses react to "WN" stimulation. Twenty-five fetuses (...

BACKGROUND Replacing carbohydrate with protein acutely increases glomerular filtration rate (GFR) but is associated with faster, long-term kidney disease progression. The effects of carbohydrate type (i.e. glycemic index, GI) on kidney function are unknown. METHODS We conducted an ancillary study of a randomized, crossover feeding trial in overweight/obese adults without diabetes or kidney di...

UNLABELLED Aims/Introduction:  To examine the association between baseline retinal vessel caliber change and prevalence, and 5-year incidence of obesity in the adult Japanese population of the Funagata study. MATERIALS AND METHODS   Of 900 individuals (age ≥ 35 years) who underwent systemic and retinal examinations in the Funagata study during 2000-2002, 584 (64.8%) were not obese as defined ...

background: initial symptoms of multiple sclerosis (ms) may be varied and nonspecific. we tried to find the frequency distribution of the first clinical symptoms in iranian patients with ms. methods: in a case series study, 1130 patients with definite diagnosis of ms who had been referred to three referral university hospitals of tehran, iran, were enrolled. the patients' medical records were r...