Uterine isthmus atresia is a rare Müllerian duct anomaly occasionally diagnosed in adolescents with primary amenorrhea and cyclic abdominal pain. A case presented of 14-year-old female monthly lower pain 2-year duration. Magnetic resonance imaging 3-dimensional ultrasound showed separation 10-mm fibrotic tissue between the cervical canal endometrial cavity. In an attempt to preserve reproductiv...

A transverse vaginal septum (TVS) is a rare Müllerian anomaly of the female genital tract [ 1 Skinner B Quint EH Obstructive reproductive anomalies: review surgical management. J Minim Invasive Gynecol. 2017; 24: 901-908 Abstract Full Text PDF PubMed Scopus (11) Google Scholar ]. The prevalence reported as 1/72 000 women 2 Dietrich JE Millar DM anomalies. Pediatr Adolesc 2014; 27: 396-402 (90) ...

During male sexual differentiation, the transforming growth factor-β (TGF-β) signaling molecule anti-Müllerian hormone (AMH; also known as Müllerian inhibiting substance, MIS) is secreted by the fetal testes and induces regression of the Müllerian ducts, the primordia of the female reproductive tract organs. Currently, the molecular identity of downstream events regulated by the AMH signaling p...

The female reproductive tract organs of mammals, including the oviducts, uterus, cervix and upper vagina, are derived from the Müllerian ducts, a pair of epithelial tubes that form within the mesonephroi. The Müllerian ducts form in a rostral to caudal manner, guided by and dependent on the Wolffian ducts that have already formed. Experimental embryological studies indicate that caudal elongati...

The assignment of the sex of rearing for patients with precocious diagnosis of ovotesticular difference of sex development (OT-DSD) is a complex decision. Ovotesticular disorder or difference of sex development (OT-DSD) is a very rare congenital anomaly characterized by the simultaneous presence of both testis and ovary in the same individual. It occurs between 3 and 10% of the total DSD (1). T...

Magnetic resonance (MR) imaging has extended the usefulness of imaging in evaluation of pelvic disorders associated with female infertility. The causes of female infertility include ovulatory disorders (ie, pituitary adenoma and polycystic ovarian syndrome), disorders of the fallopian tubes (ie, hydrosalpinx and pelvic inflammatory disease), uterine disorders (ie, müllerian duct anomaly, adenom...

Müllerian ducts can form upper parts of normal female reproductive system and any failure in ductal fusion may lead to Müllerian Duct Anomalies (MDA). We present a case of MDA, a uterus dysplasia with no evidence of cervical or upper vaginal tissue. This case illustrates the role of Magnetic Resonance Imaging (MRI) on MDA diagnosis and urges the need for a unified reliable and practical classif...