BACKGROUND Lymphatic leak and lymphocele are well-known complications after kidney transplantation. OBJECTIVE To determine the incidence of lymphatic complications in recipients of living donor kidneys. METHODS Among 642 kidney transplants performed between 1999 and 2007, the incidence of lymphatic complications was retrospectively analyzed in recipients of living donor kidneys procured by ...

BACKGROUND In lymphoscintigraphies of the head and neck, multiple injections around a tumor result in variable drainage to multiple nodal basins. We undertook this study in healthy subjects to test whether single injections at specified points in the auricle display single predictable pathways and predict visualization of parotid sentinel lymph nodes (SLNs). METHODS Twenty-five healthy subjec...

RATIONALE Lymphatic transport of peripheral interstitial fluid and dendritic cells (DCs) is important for both adaptive immunity and maintenance of tolerance to self-antigens. Lymphatic drainage can change rapidly and dramatically on tissue injury or inflammation, and therefore increased fluid flow may serve as an important early cue for inflammation; however, the effects of transmural flow on ...

Abnormal thromboscintigrams were observed in patients with lymphatic obstruction. This syndrome was reproduced by surgically ligating the lymphatic drainage of the lower extremity of a dog prior to thromboscintigraphy.

OBJECTIVE To compare the efficacy of low-frequency low-intensity electrotherapy and manual lymphatic drainage in the treatment of chronic upper limb breast cancer-related lymphoedema. DESIGN Cross-over single-blind random clinical trial. SETTING Rehabilitation service. PARTICIPANTS Thirty-six women with chronic upper limb breast cancer-related lymphoedema. METHODS Patients were randomiz...

BACKGROUND Aberrant lymphatic drainage is believed to contribute to the high recurrence rate of head and neck melanomas. The purpose of this study was to identify the clinical significance of unexpected lymphatic drainage patterns. METHODS A single institution retrospective analysis was performed of middle-aged and older men (mean age, 66.2 years; range, 41-87 years) who underwent successful ...

BACKGROUND The gynoidlypodystrophy, known as cellulitis or cellulite, refers to a condition that gives the skin an undulating and uneven appearance, affecting 80-90% of women after puberty. OBJECTIVES to investigate the efficacy and safety of manual lymphatic drainage for cellulite management. METHODS this was an open, prospective, intervention study including 20 women aged from 20 to 40 ye...

The lymphatic system provides an initial route for cancer cell dissemination in many cancers including melanoma. However, it is largely unknown how the lymphatic system changes during tumor progression due in part to the lack of imaging techniques currently available. In this study, we non-invasively imaged changes of lymphatic function and drainage patterns using near-infrared fluorescence (NI...

We demonstrate the ability to non-invasively and quantitatively image lymphatic architecture and contractile function using dynamic near-infrared (NIR) fluorescence imaging with injection of indocyanine green in normal and transgenic mice. Unlike normal mice, which showed well defined lymphatic drainage patterns and orthograde propagation of contraction waves, we observed tortuous and mispatter...

BACKGROUND The extensive mesenteric lymphadenopathy associated with midgut carcinoids often causes lymphatic obstruction and leads to the development of alternative lymphatic drainage pathways. We hypothesized that altered lymphatic drainage makes traditional determination of resection margins inadequate. METHODS One hundred and seventy patients underwent cytoreductive surgery for neuroendocr...