OBJECTIVE The purpose of this study was to compare spirometry data between patients who underwent single-lung or double-lung transplantation the first year after transplantation. INTRODUCTION Lung transplantation, which was initially described as an experimental method in 1963, has become a therapeutic option for patients with advanced pulmonary diseases due to improvements in organ conservat...

Study question In patients with sarcoidosis, past and ongoing immunosuppressive regimens, recurrent disease in the transplant extrapulmonary involvement may affect outcomes of lung transplantation. We asked whether sarcoidosis phenotypes can be differentiated and, if so, how they relate to pulmonary treated by Patients methods retrospectively reviewed data from 112 who met international diagnos...

Lung transplantation has become in recent years a therapeutic option for infants with terminal lung disease with similar results to transplantation in adults. In Spain, since 1996 114 children lung transplants have been performed; this corresponds to 3.9% of the total transplant number. The most common indication in children is cystic fibrosis, which represents between 70-80% of the transplants...

Background: Primary graft dysfunction (PGD) and acute kidney injury (AKI) are major early complications of lung transplantation associated with increased mortality. Lung after PGD can contribute to renal dysfunction; however, the association between AKI severity has not been thoroughly investigated. We analyzed grading staging, impact on subsequent changes chronic disease (CKD), including glome...

OBJECTIVES Lobar lung transplantation is an option that provides the possibility of transplanting an urgent listed recipient of small size with a size-mismatched donor lung by surgically reducing the size of the donor lung. We report our short- and long-term results with bilateral lobar lung transplantation (BLLT) and compare it with the long-term outcomes of our cohort. METHODS Retrospective...

BACKGROUND Lung transplantation has become an acceptable treatment option for many end-stage lung diseases. Pulmonary mycetomas are found in patients with end-stage lung diseases, especially sarcoidosis. The clinical course and long-term outcome of these patients after transplantation remains unknown. METHODS We reviewed retrospectively the pathology reports of the explanted lungs from all lu...

: The first lung transplant procedure in the world was performed 1983, while Japan that accomplished 1998. Over following 25 years, transplantation has become a viable treatment option for Japanese patients with variety of end-stage diseases. Seventy cadaveric-donor (41 single, 29 bilateral), 11 bilateral living-donor lobar lung, and three heart-lung transplants have been use an integrated card...

Lung transplantation offers a major survival benefit in selected patients with end-stage pulmonary disease. In recent years, there is accumulating evidence of an increase in solid organ tumors and especially in primary lung cancer. There is also some anecdotal evidence that lung transplantation may be beneficial as a treatment option in some patients with lung cancer, such as the ones with exte...

Lung transplantation offers a major survival benefit in selected patients with end-stage pulmonary disease. In recent years, there is accumulating evidence of an increase in solid organ tumors and especially in primary lung cancer. There is also some anecdotal evidence that lung transplantation may be beneficial as a treatment option in some patients with lung cancer, such as the ones with exte...

30-day mortality, PGD, BOS and long-term survival. Although we aimed at constructing a homogeneous study group (adjusting for size and diagnosis), other confounding factors might have had an influence. These circumstances might have biased the results to some degree but not, in our opinion, to an extent that may invalidate the main conclusions drawn from the study. To summarize, this single-cen...