In this article we consider a pq-dimensional random vector x distributed normally with mean vector θ and the covariance matrix Λ, assumed to be positive definite. On the basis of N independent observations on the random vector x, we wish to estimate parameters and test the hypothesis H: Λ = Ψ ⊗Σ, where Ψ = (ψij) : q × q and Σ = (σij) : p × p, and Λ = (ψijΣ), the Kronecker product of Ψ and Σ. Th...

introduction: langerhans cell histiocytosis (lch) is a rare disease characterized by clonal prolifera-tion of histiocytosis in different tissues. permanent consequences (pc) described among subjects with langerhans cell histiocytosis (lch).in this study we report the prevalence of permanent sequel among long – term survivors of lch in our center. methods: we had 30 cases of lch from 1989 – 2001...

introduction: previous studies indicate that exercise influences cognitive function. nevertheless, considering that exercise in animal study can be voluntary, or forced, effects of exercise (specially forced exercise) on learning and memory abides as a matter of controversy. the present study aimed to investigate the effects of treadmill exercise on ltp in the dentate gyrus of rats. methods: th...

where the definition of Cl( * , . , ) is obvious from above. We note that C depends explicitly on XI that contradicts the analysis in the paper’. Hence, the test which minimizes .J+, is not necessarily an LRT. For the n-stage problem ( n 2 2) , it is easily seen that p.b.p.0. local strategies at time n alone are LRT’s in general. Also, if we restrict the local decisions made by each sensor to d...

This paper reviews a decade of implementation of the public long-term care insurance (LTCI) program in Japan, which is now experiencing unprecedented pressure from its rapidly aging population. This overview of the program’s features focuses on the incentive mechanisms and diversity, and examines official future projections of LTCI costs and their accompanying assumptions. It also includes the ...