Background. Although patients with Hodgkin's lymphoma (HL) achieve prolonged survival, long-term complications are a major cause of morbidity and mortality among long-term survivors of HL. Methods. We retrospectively evaluated long-term complications in 336 HL survivors treated between January 1990 and January 2006 at the Department of Medical Oncology of the Hacettepe University Institute of O...

T he main complication of anticoagulation therapy is bleeding. We have conducted a literature review to determine: (a) the rate of bleeding during long-term anticoagulant therapy in various clinical disorders, and (b) the clinical and laboratory risk factors that predispose patients to bleeding. For the purposes of this review, we defined long-term therapy as lasting greater than 4 weeks. Hemor...

Although extensively applied in obstetrics practice to facilitate delivery by increasing the vaginal birth conduit, most episiotomy studies are in the context of short- or medium-term outcomes, and the number of studies investigating the long-term effects is insufficient. Episiotomy is often considered associated with urinary and/or anal incontinence and dyspareunia; however, there is no concre...

BACKGROUND Amiodarone hydrochloride is an antiarrhythmic agent useful in arrhythmias refractory to standard therapy. Although interstitial pneumonitis is known to be its most serious side effect, several aspects of amiodarone lung toxicity are still controversial. METHODS Pulmonary side effects were examined in a sample of 61 symptomless patients (mean (SD) age 55 (7) years) who had had long ...

Complications following pelvic radiation are frequently under-reported and inadequately addressed. This overview examines the nature and the intensity of complications encountered by cancer survivors; it focuses specifi cally on gastrointestinal and vaginal complications, and the problems surrounding the methods of recording and assessing toxicities. Peer reviewed. (Submitted: 2010-08-30, Accep...

Cryptorchidism is the most frequent defect of the male urogenital tract at birth. It represents a risk factor for primitive testiculopathy associated with long-term complications (infertility, testicular neoplasia, and hormonal changes). An only consensus exists: "children with bilateral cryptorchidism who are not treated in early age are certainly set to become infertile". The majority of Auth...

..........................................................................................................................1 Swedish summary / Svensk sammanfattning................................................................3 Original publications.......................................................................................................5 Background...................................

O the past few decades survival in patients with SLE has gradually improved in the Western world. Under optimal conditions of diagnosis and supervised treatment, with good social support, life-expectancy can be as high as 0% at 10 years.1 Although there have been a dramatic improvement in the short term prognosis with proper immunosuppression and care of infection, the mortality rates in patien...

Background: Pediatric liver transplant is a complex surgical procedure. Pediatric liver transplantation has evolved over the last two decades into an effective and widely accepted therapy for infants and children. The aim of our report is to review the current state of knowledge and explore the incidence of complications, the involved pathogens among liver recipients to determine the effective ...