Genomewide scans for mapping loci have proved to be extremely powerful and popular. We present a semiparametric method of mapping a quantitative-trait locus (QTL) or QTLs with the use of sib-pair data generated from a two-stage genomic scan. In a two-stage genomic scan, either the entire genome or a large portion of the genome is saturated with low-density markers at the first stage. At the sec...

in the present study, genotyping of six short tandem repeat (str) loci including csf1po, d16s539, f13a01, f13b, lpl and hprtb was performed on genomic dna from 127 unrelated individuals from the iranian province of isfahan. the results indicated that the allele and genotype distributions were in accordance with hardy-weinberg expectations. the observed heterozygosity (ho), expected heterozygosi...

background leptospirosis is recognized as a re-emerging infectious disease; therefore, understanding the epidemiology of the disease is vital for designing intervention programs and diminishing its transmission. recently, multilocus variable number tandem repeat analysis (mlva) is used for segregating and identifying leptospira serovars. the method has potential application in investigating the...

diversity of durum wheat (triticum turgidum ssp. durum) germplasm was evaluated using simple sequence repeat (ssr) markers. one hundred and forty durum wheat genotypes of diverse origin (belonging to ten countries) were assessed using 48 selected ssrs with whole genome coverage. a total of 245 allelic variants were detected at 37 polymorphic ssr loci, ranging from two to seventeen per locus wit...

Objective(s): Short tandem repeat (STR) loci are the most informative DNA genetic markers for attempting to individualize biological material for application in paternity and forensic cases. Materials and Methods: Blood samples were collected and the total genomic DNA was extracted. The DNA samples were used for genotyping VWA and TPOX STR loci using PCR and polyacrylamide gel electrophoresis. ...