multiple sclerosis (ms) is an autoimmune disease of central nervous system. since different types of immune cells are involved in ms pathogenesis, in this study we aimed to evaluate serum levels of several immunological components including soluble cd4 (scd4), scd8, scd163, and immunoglobulins as markers of activity of t-cells, macrophages, and b-cells in different types of ms. serum levels of ...

Oral tolerance is a physiological immune mechanism, which controls the outcome of deleterious hypersensitivity reactions to environmental antigens absorbed through the gastrointestinal tract, and maintains homeostasis. Using a mouse model of oral tolerance of delayed type hypersensitivity to contact allergens, i.e. haptens, we have examined the mechanisms involved in the induction of oral toler...

A group is said to be acyclic if its reduced homology vanishes. Many interesting classes of groups have been discovered having this property ([2] is a useful survey). This is an indication that the reduced homology carries limited information. Here we obtain information about H̃(G) for a class of groups G that includes all locally finite groups and all soluble groups of finite rank. We show that...

this is a survey article on centralizers of finite‎ ‎subgroups in locally finite‎, ‎simple groups or lfs-groups as we‎ ‎will call them‎. ‎we mention some of the open problems about‎ ‎centralizers of subgroups in lfs-groups and applications of the‎ ‎known information about the centralizers of subgroups to the‎ ‎structure of the locally finite group‎. ‎we also prove the‎ ‎following‎: ‎let $g$ be...

Locally Decodable codes(LDC) support decoding of any particular symbol of the input message by reading constant number of symbols of the codeword, even in presence of constant fraction of errors. In a recent breakthrough [9], Yekhanin constructed 3-query LDCs that hugely improve over earlier constructions. Specifically, for a Mersenne prime p = 2−1, binary LDCs of length 2O(n1/t) for infinitely...

A group is called extended residually finite (ERF) if every subgroup is closed in the profinite topology. The ERF-property is studied for nilpotent groups, soluble groups, locally finite groups and FC-groups. A complete characterization is given of FC-groups which are ERF. 2000 Mathematics Subject Classification: Primary 20E26.

Immunostimulatory therapies that activate immune response pathways are of great interest for overcoming the immunosuppression present in advanced tumors. Agonistic anti-CD40 antibodies and CpG oligonucleotides have previously demonstrated potent, synergistic anti-tumor effects, but their clinical use even as monotherapies is hampered by dose-limiting inflammatory toxicity provoked upon systemic...

Following an active period of policy development and implementation in the 1990s,1 there have been two national great leaps forward that tackled geographical health inequalities in Australia in the new century. In 2000, in the context of growing disaffection in the rural electorate,2 the then health minister, Michael Wooldridge, was responsible for a federal Budget centrepiece of $562 million, ...