this paper deals with local buckling analysis of rectangular functionally graded material plates using finite strip method and based on classical plate theory. the modulus of elasticity of the plate is assumed to vary according to a power-law distribution in terms of the volume fractions of the constituents. the principle of minimum total potential energy is employed to obtain stiffness and sta...

upflow anaerobic sludge blanket (uasb) reactors have been widely used for treatment of industrial wastewater. in this study, performance of a lab-scale up-flow anaerobic sludge blanket (uasb) reactor, treating a chemical synthesis-based pharmaceutical wastewater, was evaluated under different operating conditions. a (p.e) pipe with a diameter of 250 mm and total height of 120 cm and effective h...

Background: It is believed that the loading value of anticancer drug conjugated to the monoclonal antibody, called drug-to-antibody ratio (DAR), is the main quality feature of antibody-drug conjugates. Methods: In this study, matrix assisted laser desorption/ionization mass spectrometry was used to determine the average molecular weight of trastuzumab and its three conjugated forms. The differe...

Noninvasive assessment of intestinal permeability in vivo is based on the measurement of urinary excretion of orally administered sugar probes. It is expressed as a ratio, usually lactulose/rhamnose or 3-O-methyl-D-glucose (3-OMG)/rhamnose. In both endotoxemic and control rats that were receiving fluid, we observed an increase in the recovery of lactulose and 3-OMG but not rhamnose in both grou...

Physical inactivity leads to muscle atrophy and capillary regression in the skeletal muscle. Intermittent loading during hindlimb unloading attenuates the muscle atrophy, meanwhile the capillary regression in the skeletal muscle is not suppressed. Nucleoprotein has antioxidant capacity and may prevent capillary regression. Therefore, we assessed the combined effects of intermittent loading with...