نتایج جستجو برای: lncrna pvt1
تعداد نتایج: 7130 فیلتر نتایج به سال:
This study evaluated the lnc-RNAs as biomarker to predict efficacy of gemcitabine (GEM) based chemotherapy as the first-line treatment for locally advanced or advanced pancreatic cancer patients. We selected 62 patients with GEM based chemotherapy and divided two groups according to the PFS. We found that the expression of MALAT1, HOTTIP, and PVT1 in serum had a significant difference among the...
The marine bacterium Vibrio tapetis is the causative agent of the brown ring disease, which affects the clam Ruditapes philippinarum and causes heavy economic losses in North of Europe and in Eastern Asia. Further characterization of V. tapetis isolates showed that all the investigated strains harbored at least one large plasmid. We determined the sequence of the 82,266 bp plasmid pVT1 from the...
PVT1 was originally identified as a transcriptional unit from a human homologous sequence to Pvt1, which was cloned from murine plasmacytoma with t(6;15). Previous studies have revealed various genetic alterations in the PVT1 locus, including chromosome translocation, amplification, chromothripsis, and single nucleotide polymorphisms in human diseases, suggesting important roles of PVT1 in the ...
The PVT1 locus is identified as a cluster of T(2;8) and T(8;22) "variant" MYC-activating chromosomal translocation breakpoints extending 400 kb downstream of MYC in a subset (approximately 20%) of Burkitt's lymphoma (vBL). Recent reports that microRNAs (miRNA) may be associated with fragile sites and cancer-associated genomic regions prompted us to investigate whether the PVT1 region on chromos...
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