We extend the Langevin Monte Carlo (LMC) algorithm to compactly supported measures via a projection step, akin to projected Stochastic Gradient Descent (SGD). We show that (projected) LMC allows to sample in polynomial time from a log-concave distribution with smooth potential. This gives a new Markov chain to sample from a log-concave distribution. Our main result shows in particular that when...

Leptomeningeal cancer (LMC), which refers to involvement of the cerebrospinal fluid by cancer cells, is a poor prognostic sign that complicates various solid malignancies. Treatment of LMC evolved around brain radiation, intrathecal therapy, and systemic chemotherapy, but response rates are unsatisfactory, and patients usually die from cancer progression. In this article, we review the history ...

We examine the morphology of the color-magnitude diagram (CMD) for core helium-burning (red clump) stars to test the recent suggestion by Zaritsky & Lin (1997) that an extension of the red clump in the Large Magellanic Cloud (LMC) toward brighter magnitudes is due to an intervening population of stars that is responsible for a significant fraction of the observed microlensing toward the LMC. Us...

During embryonic development, the generation, diversification and maintenance of spinal motor neurons depend upon extrinsic signals that are tightly regulated. Retinoic acid (RA) is necessary for specifying the fates of forelimb-innervating motor neurons of the Lateral Motor Column (LMC), and the specification of LMC neurons into medial and lateral subtypes. Previous studies implicate motor neu...

There are lines of evidence suggesting that some of the observed microlensing events in the direction of the Large Magellanic Cloud (LMC) are caused by ordinary star lenses as opposed to dark MACHOs in the Galactic halo. Efficient lensing by ordinary stars generally requires the presence of one or more additional concentrations of stars along the line of sight to the LMC disk. If such a populat...

There are lines of evidence suggesting that some of the observed microlensing events in the direction of the Large Magellanic Cloud (LMC) are caused by ordinary star lenses as opposed to dark Machos in the Galactic halo. Efficient lensing by ordinary stars generally requires the presence of one or more additional concentrations of stars along the line of sight to the LMC disk. If such a populat...

Prolonged cultivation of separated rat lung mast cells (LMC) in vitro is necessary to better investigate a possible role of LMC in different stages of tissue remodeling induced by hypoxia. Rat lung mast cells (LMC) were separated using a protocol including an improved proteolytic extraction and two subsequent density gradient separations on Ficoll-Paque PLUS and a new generation of Percoll, i.e...

We present a new analysis on the issue of the location of the observed microlensing events in direction of the Large Magellanic Cloud (LMC). This is carried out starting from a recently drawn coherent picture of the geometrical structure and dynamics of the LMC disk and by considering different configurations for the LMC bar. In this framework it clearly emerges that the spatial distribution of...

We examine the morphology of the color-magnitude diagram (CMD) for core helium-burning (red clump) stars to test the recent suggestion by Zaritsky & Lin (1997) that an extension of the red clump in the Large Magellanic Cloud (LMC) toward brighter magnitudes is due to an intervening population of stars that is responsible for a significant fraction of the observed microlensing toward the LMC. Us...

There is strong evidence that the period-luminosity (PL) relation for the Large Magellanic Cloud (LMC) Cepheids shows a break at a period around 10 days. Since the LMC PL relation is extensively used in distance scale studies, the non-linearity of the LMC PL relation may affect the results based on this LMC calibrated relation. In this paper we show that this problem can be remedied by using th...