The modulating effect of five dose levels of butylated hydroxytoluene (BHT) on liver and bladder carcinogenesis induced in rats by concurrent exposure to 2-acetylaminofluorene (AAF) was investigated. AAF at a low dose of 50 ppm was fed simultaneously with concentrations of 100, 300, 1000, 3000, or 6000 ppm BHT in the diet to male F344 rats for up to 76 weeks. By 12 weeks, AAF alone induced alte...

Malignant neoplasms diagnosed histologically in the state of Sabah during the period November 1983 to October 1988 were analysed to determine the distribution of malignant neoplasms according to site, age, sex and major ethnic groups. The five commonest malignant neoplasms in males were carcinomas of the nasopharynx, stomach, skin, lung and liver. In females the five commonest malignant neoplas...

Of 291 juvenile and adult snakes examined post mortem over a 20-year period (1978-1997) at the National Zoological Park (NZP) in Washington, DC, 36 (24 females and 12 males) had neoplasms. Two snakes had tumours of two or three different types, but the other 34 snakes had only one type. All affected animals were adults and their average time on exhibit at the NZP was 108-9 months. Malignant neo...

During chemical carcinogenesis in the liver, a population of abnormal cells in lesions referred to as altered foci precedes the appearance of neoplasms. Most altered foci do not develop further, but a small fraction progress to formation of neoplasms. Liver tumor promoters increase the fraction that progress. The mechanisms for this action of promoters may involve an effect on the cell membrane...

Cystic lesions originating from the gallbladder are very rare. Mucinous cystic neoplasms of liver and biliary system principally occur in liver, followed by extrahepatic system. Only a few case reports were reported primarily gallbladder. A 63-year-old woman was admitted to our hospital with complaints pain right upper abdomen, increasing after meals, abdominal discomfort. laparoscopic cholecys...

A series of field studies was conducted between 1979 and 1985 in Puget Sound, Washington State, to investigate etiological relationships between prevalences of hepatic neoplasms in bottom-dwelling marine fish species, with emphasis on English sole (Parophrys vetulus), and concentrations of toxic chemicals in sediments and affected fish. Statistically significant (p less than or equal to 0.05) c...

The Aim . Study of a clinical case metachronous primary multiple cancer the head pancreas and liver. Materials methods work was carried out with modern domestic foreign literature sources devoted to problem malignant neoplasms. A retrospective analysis patient’s anamnestic data performed, necessary medical documentation studied. Results In 2011, pancreatoduodenal resection performed on patient ...

BACKGROUND Radiofrequency thermal ablation (RFA) has been demonstrated to be useful for the treatment of liver neoplasms. The study aimed to evaluate the feasibility and safety of the combination of transarterial chemoembolization (TACE) and RFA, performed simultaneously to treat primary and secondary liver neoplasms. PATIENTS AND METHODS From July 2006 to October 2007, 34 patients (21 with H...

Fanconi anemia, an autosomal recessive and X-linked disorder, is known to be associated with a variety of neoplasms. Liver tumors are one of the most frequently observed neoplasms but the association between the two disorders remains obscure. We present a case of a 27-year old female Fanconi anemia patient diagnosed with a mass on the right lobe of the liver measuring 90x75x60 mm. Histopatholog...

with open hepatectomy. The indications for LH have gradually expanded, from local resection of benign neoplasms at the liver edge to hemihepatectomy and more extensive anatomical resections, segmentectomy for malignant neoplasms, and donor hepatectomy for liver transplantations. The numbers of LH procedures performed are increasing exponentially in surgical centers worldwide [1,2]. In some high...