introduction: various radiopharmaceuticals, including 67ga, 201tl, and 99mtc-sestamibi have been used to differentiate benign from malignant thyroid nodules. 99mtc-tetrofosmin, a lipophilic cationic radiotracer, and 99mtc-sestamibi have also been reported to accumulate in thyroid tumors. in this study, we evaluated the role of 99mtc-tetrofosmin in the differentiation of malignant from benign th...

Thyroid ultrasound is used in the routine clinical assessment and the follow-up of thyroid disorders. The follow- up of patients with thyroid nodules is mostly based on thyroid nodule volume determinations performed by different observers. However, for the judgment of treatment effects there is uncertainty about the interobserver variation of thyroid nodule volume measurements by ultrasound bec...

CONTEXT Endemic area and iodine supplementation may affect the pathogenesis of the nodule which commonly occurs in endemic thyroid enlargement due to iodine deficiency. AIMS To establish pathological changes in solitary solid and larger nodule of the thyroid in endemic area. SETTING AND DESIGN Retrospective study in Surgical Department of University Hospital. METHODS AND MATERIAL We deter...

Current computer-aided diagnosis (CAD) models for determining pulmonary nodule malignancy characterize nodule shape, density, and border in computed tomography (CT) data. Analyzing the lung parenchyma surrounding the nodule has been minimally explored. We hypothesize that improved nodule classification is achievable by including features quantified from the surrounding lung tissue. To explore t...

AIM To describe two new ultrasound signs for thyroid nodules - "nodule in nodule" and "hypoechoic internal septae" and assess their usefulness in differentiating follicular variant of papillary thyroid carcinoma (FVPTC) from benign thyroid nodules (BTN). METHODOLOGY Ultrasound findings of 210 patients with histopathologically proven FVPTC (68 nodules, M:F=13:47 with mean age of 39.5±11.9 year...

Nodule formation on ITO sputtering targets was investigated by stop action in-situ video observation, 3D-SIMS, and EPMA. Major cause of nodule formation is particulates from the sputtering system, less important are particulate inclusions in the target material. A nodule growth mechanism and strategies to minimize nodule formation are proposed.

We present two cases of solitary necrotic nodules of the liver which on radiologic images mimicked hepatic metastasis. Solitary necrotic nodule of the liver is a rare but benign entity which histopathologically consists of an outer fibrotic capsule with inflammatory cells and a central core of amorphous necrotic material. The lesion was seen on contrast-enhanced CT as an ovoid-shaped hypoattenu...

In 30 patient with single cold thyroid nodule and normal thyroid function tests, 99mTc-MIBI scan is performed. The nodules are divided to hot (10), Warm (12) and cold (8). FNA reported papillary Ca in 4, suspicious follicular neoplasm in 3 and 23 benign lesions. 7 patients were operated on and had final pathology reports (4 papillary Ca and 3 benign lesions). All the nodules with no MIBI ...

A 63-year-old woman presented with a history of hyperthyroidism symptoms over two years, referred for thyroid scintigraphy. In the hospital archives we have met her previous thyroid scintigraphy showing a hot nodule in the upper part of right thyroid lobe. However, her recent thyroid scintigraphy was showing only cold nodules but no hot nodule, giving an impression that she had some treatment t...