The in vitro dissolution property of slightly water soluble Fenofibrate (FN) was improved by exploring the potential of Liquisolid system (LS). The in vitro release pattern of LS compacts and directly compressed tablets were studied using USP-II apparatus. Different LS compacts were prepared using a mathematical model to calculate the required quantities of powder and liquid ingredients to prod...

Resveratrol is a class II drug in the Biopharmaceutics Classification System (BCS) with poor water solubility (0.03 mg/ml) and high permeability. Liquisolid system an innovative technique used for enhancing dissolution rate bioavailability of poorly soluble drugs. The present study demonstrated that loaded SNEDDS compacts were successfully developed. Ten formulation formulated different ratio o...

Objective: The current research is aimed to enhance the dissolution and bioavailability of Palbociclib by formulating into solid dispersion Methods: dispersions (SD) prepared adopting different methods: Surface technique (SSD1-SSD15), Melt granulation (MG1-MG15) Liquisolid compacts (LSC1-LSC9). All formulations were evaluated for physico-chemical parameters followed in vitro studies. optimised ...

Aims: The main objective of the current research work is to develop liquisolid compacts BCS Class II drug ketoprofen with an intention enhance solubility by applying technique.
 Place and Duration Study: Smriti College Pharmaceutical Education between June 2018 2019.
 Methodology: Initially liquid medication was obtained dissolving in suitable solvent. Saturation studies were performe...

To overcome the limitations of the conventionally used methods for evaluation of orally administered colon-targeted delivery systems, a novel dissolution method using probiotics has been recently reported. In the present study, universal suitability of this medium composed of five different probiotics is established. Different delivery systems - mini tablets, liquisolid compacts, and microspher...

The aim of present study was to improve the solubility of pioglitazone HCl a practically insoluble antidiabetic drug by using liquisolid technique. The in vitro release pattern of liquisolid tablets and directly compressed tablets were studied using USP-II apparatus. Different Liquisolid tablets were prepared using a mathematical model to calculate the required quantities of powder and liquid i...

The main objective of this study is to improve the dissolution and there by availability of Irbesartan a practically insoluble drug by liquisolid Compact technique. The liquisolid tablets of Irbesartan were prepared by using various ratio of carrier (Avicel PH 102) to coating (Cab-O-Sil M5) material using PEG 400 as non volatile solvent. The prepared liquisolid tablets were evaluated for hardne...