metronidazole, a synthetic derivative of the nitroimidazole class is a known antibacterial and antiprotozoal agent. the hypolipidemic effect of metronidazole was not known. the authors noticed it incidentally for the first time. after quazi experimental studies on several cases, it was revealed that 750 mg of metronidazole for 10 days significantly decreased serum cholesterol. this trial was pe...

microbial oil has high similarity to the oil obtained from plants and animals. they are renewable sources that can be used for different purposes such as production of biofuels. biofuels are renewable, biodegradable, and nontoxic, which makes them highly environmentally friendly. producing oil from yeasts has more advantages than that from plants. accordingly, isolation of oleaginous yeasts wit...

fasting induces short-term physiological adaptations which spare the body's remaining carbohydrate stores and mobilize lipid stores to provide a substitute fuel for many tissues and organs, especially skeletal muscle. rodent studies show that regular occurrence of fasting then refeeding, stimulates adaptations in muscle which make the animal better placed to withstand a further period of fastin...

introduction: during ramadan, type and amount of energy intake dramatically change in muslims and fasting individuals often reduce the duration and intensity of physical activities or avoid exercise during this month. however, one of the major issues of trainers and athletes is lack of training, which could have adverse effects on some cardiovascular parameters. methods: this research was condu...

malondialdehyde (mda) is widely used as a biomarker for assessing oxidative stress in biomedical fields. lipid peroxidation is a chain phenomenon resulting in the formation of various active compounds that result in cellular damage. biomonitoring of mda has been used in both in-vivo and in-vitro studies as a key biomarker for various disease patterns including hypertension, diabetes, atheroscle...

abstract the objective of present study was to evaluate pharmacokinetic parameters of dibudipine phytosolve after oral administration in rats. the solubility test was carried out to select suitable oily solvent for dibudipine. phytosolve formulation was prepared with a medium chain triglyceride (mct) oil (20%), soybean phospholipids (5%) and a 70% fructose solution (75%). the effect of polyol c...

uterine sarcoma is a rare tumor of mesodermal origin, accounting for 2-6% of uterine malignancies. leiomyosarcoma (lms) has been reported in only 1% of all uterine malignancies and is regarded as the most common primary uterine sarcoma. herein, we present a case of lms with unusual macroscopic features. the patient was a 61-year-old woman with lms, which consisted of a large cystic mass (88×136...

large unilamellar liposomes and multilamellar vesicles consisting of dmpc interacted with cationic phosphorus-containing dendrimers cpds g3 and g4. dsc and ζ -potential measurements have shown that liposomal-dendrimeric molecular recognition occurs due to the interaction between the complementary surface groups. calorimetric studies indicate that the enthalpy of the transition of the lipids tha...

aloe vera has been used worldwide in pharmaceutical, food and cosmetic industries due to the plethora of biological activities of its constituents. this study was done to evaluate the effects of dietary aloe vera on growth and lipid peroxidation in rainbow trout (oncorhynchus mykiss). a total number of 480 o. mykiss (mean weight 9.50 ± 0.85 g) were randomized into four experimental groups inclu...

the objective of this study was to evaluate effect of different concentrations of catalase in two extenders on motility, viability and lipid peroxidation bull spermatozoa during semen freezing process. thirty ejaculates collected from ten holstein bulls were pooled and evaluated at 37 °c. pool ejaculated was split into two main experimental groups, 1 and 2. in experiment 1, specimen was diluted...