We use wavelength tunable femtosecond pulses to measure intrinsic (simultaneous) two-photon absorption (2PA) and three-photon absorption (3PA) molecular cross section in two series of p-conjugated dendrimers built of identical 4,40-bis(diphenylamino) stilbene (BDPAS) and 4,40-bis(diphenylamino) distyrylbenzene (BDPADSB) repeat units. Record large 2PA cross sections, s2=10 46 cm s are obtained f...

Atomistic molecular dynamics simulations have been carried out to reveal the characteristic features of ethylenediamine (EDA) cored protonated (corresponding to neutral pH) poly amido amine (PAMAM) dendrimers of generation 3 (G3) and 4 (G4) that are functionalized with single stranded DNAs (ssDNAs). The four ssDNA strands that are attached via alkythiolate [-S (CH2)6-] linker molecule to the fr...

We have designed a new type of a DNA dendrimer which has rigid branched structure. The branching molecule was prepared from 1,3,5-tribromobenzene. The dendrimer unit, in which three oligonucleotide-chains, two molecules of T15 and one molecule of A15, linked to the branching molecule, was synthesized by an automated DNA synthesizer. The properties of the dendrimer unit and dendrimer formation b...

The nature of one and two-photon absorption enhancement in a series of oligothiophene dendrimers, recently proposed for applications in entangled photon sensors and solar cells, has been analyzed using both theory (time dependent density functional theory calculations) and experiment (fluorescence upconversion measurements). The linear absorption spectra exhibit a red shift of the absorption ma...

Nanomedicine represents a very significant contribution in current cancer treatment; addition to surgical intervention, radiation and chemotherapeutic agents that unfortunately also kill healthy cells, inducing highly deleterious often life-threatening side effects the patient. Of numerous nanoparticles used against cancer, gold had been developed for therapeutic applications. Inter alia, large...

The antitumor effect of doxorubicin (DOX) conjugated to a biodegradable dendrimer was evaluated in mice bearing C-26 colon carcinomas. An asymmetric biodegradable polyester dendrimer containing 8-10 wt % DOX was prepared. The design of the dendrimer carrier optimized blood circulation time through size and molecular architecture, drug loading through multiple attachment sites, solubility throug...

BACKGROUND Polyamidoamine (PAMAM) and polypropylenimine (PPI) dendrimers are the commercially available and most widely used dendrimers in pharmaceutical sciences and biomedical engineering. In the present study, the loading and release behaviors of generation 3 PAMAM and generation 4 PPI dendrimers with the same amount of surface amine groups (32 per dendrimer) were compared using phenylbutazo...

We have synthesized a novel amphiphilic naphthalene imide bearing a cationic dendrimer wedge (NID). NID molecules in water self-assemble to form a two-dimensional ribbon, which further coils to give a linear supramolecular nanofiber. The sample solution showed linear dichroism (LD) upon stirring of the solution, where NID nanofibers dominantly align at the center of vortex by hydrodynamic inter...

Abstract: structures in alloys. This method is based on pouring the melt through a small sized nozzle into a mould located at acertain height under the crucible. This simple method generates globular structures without using equipments such asimpellers, electromagnetic stirrers, ultrasonic probes and cooling slopes. Therefore it is cost effective. In the presentstudy, the effect of casting size...