TO THE EDITOR—We read with interest the article entitled " Is Fidaxomicin Worth the Cost? An Economic Analysis, " by Bartsch et al [1]. The analytical methods used by the authors seem appropriate for the research question posed. However, several assumptions are not appropriate. The authors assumed that a second course of therapy is cura-tive, with no chance of recurrence. That means that a rela...

A group of previously untreated obese hypertensive patients were started on a weight reduction programme supervised by two dietitians working in a general practice surgery. It was stressed from the beginning of the programme that reducing blood pressure was the purpose of the diet. The results of follow-up after six months are presented together with results for a control group of obese hyperte...

despite best efforts, concern remains about potential variations in rectal cancer treatment and outcomes. The System Performance Initiative at the Canadian Partnership Against Cancer regularly reports on standardized indicators at a national level to help identify opportunities for pan-Canadian system improvements. Recognizing that surgical resection is generally recommended as first-line treat...

The rise of resistance together with the shortage of new broad-spectrum antibiotics underlines the urgency of optimizing the use of available drugs to minimize disease burden. Theoretical studies suggest that coordinating empirical usage of antibiotics in a hospital ward can contain the spread of resistance. However, theoretical and clinical studies came to different conclusions regarding the u...