نتایج جستجو برای: like growth factor

تعداد نتایج: 2001391  

2015
Paolo Giovanni Vigneri Elena Tirrò Maria Stella Pennisi Michele Massimino Stefania Stella Chiara Romano Livia Manzella

The insulin/insulin-like growth factor (IGF) system is a major determinant in the pathogenesis and progression of colorectal cancer (CRC). Indeed, several components of this signaling network, including insulin, IGF-1, IGF-2, the IGF-binding proteins, the insulin receptor (IR), the IGF-1 receptor (IGF-1R), and IR substrate proteins 1 and 2 contribute to the transformation of normal colon epithe...

Journal: :The Journal of bone and joint surgery. British volume 2002
C A Beeton R A Brooks D Chatfield M Human N Rushton

There is evidence to suggest that fractures heal more rapidly in patients with a head injury as a result of systemic factors released from the site of this injury. We have measured the circulating level of insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 (IGFBP-3) in serum because of their known involvement in the stimulation of the activity of osteoblasts and the healing of fract...

Journal: :British Journal of Cancer 2006

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