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A diallel cross is a set of all possible matings between several genotypes, which may be individuals, clones, homozygous lines, etc. Such crosses are used to estimate general and specific combining abilities of lines and crosses respectively. For ‘n’ inbreed lines, the possible F1’s are n(n–1)/2, which are to be tested in a suitably replicated randomized design. With facilities available for te...

BACKGROUND The 2 × 2 factorial design is widely used for assessing the existence of interaction and the extent of generalizability of two factors where each factor had only two levels. Accordingly, research problems associated with the main effects and interaction effects can be analyzed with the selected linear contrasts. METHODS To correct for the potential heterogeneity of variance structu...

A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS) was successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a poorly water-soluble drug, while reducing the total quantity for administration. Poloxamer 407 is a selectable, supersaturating agent for VST-containing SMEDDS composed of 10% Capmul® MCM, 45% Tween® 20, and 45% Transcutol...

Factorial designs have broad applications in agricultural, engineering and scientific studies. In constructing and studying properties of factorial designs, traditional design theory treats all factors as nominal. However, this is not appropriate for experiments that involve quantitative factors. For designs with quantitative factors, level permutation of one or more factors in a design matrix ...

In the current study, the sources of variation in the mean hardness value of heat treated aluminum 2024 samples were identified by using metallurgical study and design of experiment methodology (full factorial method). Hardness measurements and microstructural investigations of the samples were carried out using Brinell hardness test and optical microscopy, respectively. The effects of several ...