نتایج جستجو برای: leukocyte telomere length

تعداد نتایج: 346584  

Journal: :The American Journal of Cardiology 2015

2011
Owen M. Wolkowitz Synthia H. Mellon Elissa S. Epel Jue Lin Firdaus S. Dhabhar Yali Su Victor I. Reus Rebecca Rosser Heather M. Burke Eve Kupferman Mariana Compagnone J. Craig Nelson Elizabeth H. Blackburn

BACKGROUND Depression is associated with an unusually high rate of aging-related illnesses and early mortality. One aspect of "accelerated aging" in depression may be shortened leukocyte telomeres. When telomeres critically shorten, as often occurs with repeated mitoses or in response to oxidation and inflammation, cells may die. Indeed, leukocyte telomere shortening predicts early mortality an...

2017
Yuji Aoki Masato Aoki Kazuya Yamada

Leukocyte telomere length and serum levels of high-molecular-weight adiponectin and dehydroepiandrosterone-sulfate (DHEA-S) were assessed in association with nutrition and performance status (PS) in Japanese centenarians. Twenty-three centenarians (five men, 18 women) were classified according to their PS 1 (nearly fully ambulatory, n = 2), 2 (in bed less than 50% of daytime, n = 10), 3 (in bed...

2013
Joshua Denham Christopher P. Nelson Brendan J. O’Brien Scott A. Nankervis Matthew Denniff Jack T. Harvey Francine Z. Marques Veryan Codd Ewa Zukowska-Szczechowska Nilesh J. Samani Maciej Tomaszewski Fadi J. Charchar

Telomere length is recognized as a marker of biological age, and shorter mean leukocyte telomere length is associated with increased risk of cardiovascular disease. It is unclear whether repeated exposure to ultra-endurance aerobic exercise is beneficial or detrimental in the long-term and whether it attenuates biological aging. We quantified 67 ultra-marathon runners' and 56 apparently healthy...

Journal: :Aging cell 2006
S Demissie D Levy E J Benjamin L A Cupples J P Gardner A Herbert M Kimura M G Larson J B Meigs J F Keaney A Aviv

Insulin resistance and oxidative stress are associated with accelerated telomere attrition in leukocytes. Both are also implicated in the biology of aging and in aging-related disorders, including hypertension. We explored the relations of leukocyte telomere length, expressed by terminal restriction fragment (TRF) length, with insulin resistance, oxidative stress and hypertension. We measured l...

2016
Rui Zhang Jian Zhao Jian Xu Fang Liu

There is increasing evidence supporting the role of telomeres in cancer pathogenesis. However, limited studies have investigated the association between telomere length features and risk of pancreatic cancer and colorectal cancer (CRC), and little was conducted in Asians. To help clarify this issue, We measured relative peripheral leukocytes telomere length (LTL) and telomere length variation (...

Journal: :Hypertension 2009
Zhiwei Yang Xin Huang Hong Jiang Yanrong Zhang Hongxia Liu Chuan Qin Gilbert M Eisner Pedro A Jose Lenhard Rudolph Zhenyu Ju

Aging is a major risk factor for hypertension and cardiovascular disease. Accumulating evidence suggests that telomere length is a marker for biological aging of the cardiovascular system. Telomere length is determined by genetic and environmental factors. Studies in different racial populations are required to determine the prognostic value of telomere length in hypertension and cardiovascular...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید