Persistant hyperplastic primary vitreous (PHPV) was described in detail as a clinical entity by Reese1 in 1955 in his Jackson Memorial Lecture. Goldberg in his 1997 Jackson Memorial Lecture2 renamed PHPV as persistent fetal vasculature (PFV). PHPV is a pathologic entity resulting from abnormal persistence of the fetal fibrovascular primitive stroma (hyaloid system) of the eye3,4 which should di...

INTRODUCTION Several aspects of retinoblastoma in Nepal remain enigmatic. OBJECTIVE To assess the demographic and geographic distribution, clinical presentation, and treatment methods of retinoblastoma at a tertiary level ophthalmic institution in Kathmandu, Nepal. MATERIALS AND METHODS A retrospective analysis of all the patients diagnosed with retinoblastoma at Tilganga Institute of Ophth...

Results The incidence of retinoblastoma increased from 40/100,000 new cases in 1967 to 1977 to 237/100,000 new cases in 1997 to 2001. The average age at onset did not change over time but the age at consultation decreased from 1.5 years to 1 year. The most common initial ocular manifestation at onset was cat’s eye reflex (77 to 79%) with findings of leukocoria (67 to 77%). Extraocular findings ...

Background: Retinoblastoma is the most common embryonic tumor of retina of children. This tumor include 3-4% of all children malignancies during the age range 0-14 years. In this study, we reported the incidence, therapeutic protocols, and treatment outcome of children with RB in South west Iran. Methods: We retrospectively investigated the medical reports clinical and pathological features of...

Purpose Leukocoria is the most common presenting sign for pediatric eye disease including retinoblastoma and cataract, with worse outcomes if diagnosis is delayed. We investigated whether individuals could identify leukocoria in photographs (photoleukocoria) and examined their subsequent Internet search behavior. Methods Using a web-based questionnaire, in this cross-sectional study we invite...

BACKGROUND Retinobalstoma, the commonest childhood malignant intraocular tumour, is usually diagnosed early with over 90% survival rate in developed countries. In developing countries, the diagnosis is late resulting in less than 50% survival. OBJECTIVE To determine retinoblastoma stages at presentation and patients' outcomes. DESIGN Retrospective case series. METHODS The clinical and his...

To study the clinical presentation and treatment outcome among children in South Western China with retinoblastoma (RB) and to determine factors predictive of poor outcome.A retrospective review of children diagnosed with RB from 2006 to 2015 at West China Hospital was undertaken. Demographic and clinical characteristics and treatment outcomes were studied.A total of 253 patients (unilateral 80...