نتایج جستجو برای: lesions volume

تعداد نتایج: 476769  

Journal: :Antimicrobial agents and chemotherapy 2012
Laura E Via Dan Schimel Danielle M Weiner Veronique Dartois Emmanuel Dayao Ying Cai Young-Soon Yoon Matthew R Dreher Robin J Kastenmayer Charles M Laymon J Eoin Carny Joanne L Flynn Peter Herscovitch Clifton E Barry

With a host of new antitubercular chemotherapeutics in development, methods to assess the activity of these agents beyond mouse efficacy are needed to prioritize combinations for clinical trials. Lesions in Mycobacterium tuberculosis-infected rabbits are hypoxic, with histopathologic features that closely resemble those of human tuberculous lesions. Using [(18)F]2-fluoro-deoxy-d-glucose ([(18)F...

Journal: :Journal of neurology, neurosurgery, and psychiatry 2000
N Stocchetti M Croci D Spagnoli F Gilardoni F Resta A Colombo

OBJECTIVE To assess the clinical feasibility and the accuracy of two pragmatic methods in comparison with a conventional computer based method of measurement of masses from CT. METHODS Nineteen CT scans of 11 patients with severe head injury, showing 34 traumatic lesions, were examined. The volume of every lesion was digitally measured, then a panel of three examiners independently repeated t...

Journal: :Journal of the American College of Cardiology 2013
Ryo Nakazato Aryeh Shalev Joon-Hyung Doh Bon-Kwon Koo Heidi Gransar Millie J Gomez Jonathon Leipsic Hyung-Bok Park Daniel S Berman James K Min

OBJECTIVES This study examined the performance of percent aggregate plaque volume (%APV), which represents cumulative plaque volume as a function of total vessel volume, by coronary computed tomography angiography (CTA) for identification of ischemic lesions of intermediate stenosis severity. BACKGROUND Coronary lesions of intermediate stenosis demonstrate significant rates of ischemia. Coron...

Journal: :Stroke 2006
Christian Opherk Nils Peters Markus Holtmannspötter Andreas Gschwendtner Bertram Müller-Myhsok Martin Dichgans

BACKGROUND AND PURPOSE The phenotypic expressivity shows striking variability among individuals with CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), a small vessel disease caused by mutations in NOTCH3. However, little is known about the factors that underlie this variability. We sought to quantify the contribution of modifying genetic effec...

Journal: :Human brain mapping 2012
Marco Battaglini Mark Jenkinson Nicola De Stefano

MR-based measurements of brain volumes may be affected by the presence of white matter (WM) lesions. Here, we assessed how and to what extent this may happen for WM lesions of various sizes and intensities. After inserting WM lesions of different sizes and intensities into T1-W brain images of healthy subjects, we assessed the effect on two widely used automatic methods for brain volume measure...

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