نتایج جستجو برای: length human

تعداد نتایج: 1912885  

2018
Jingjing Duan Zongli Li Jian Li Ana Santa-Cruz Silvia Sanchez-Martinez Jin Zhang David E Clapham

Transient receptor potential melastatin subfamily member 4 (TRPM4) is a widely distributed, calcium-activated, monovalent-selective cation channel. Mutations in human TRPM4 (hTRPM4) result in progressive familial heart block. Here, we report the electron cryomicroscopy structure of hTRPM4 in a closed, Na+-bound, apo state at pH 7.5 to an overall resolution of 3.7 Å. Five partially hydrated sodi...

Journal: :Investigative ophthalmology & visual science 2004
Richard A Stone Graham E Quinn Ellie L Francis Gui-shuang Ying D Ian Flitcroft Parag Parekh Jamin Brown Joshua Orlow Gregor Schmid

PURPOSE This study sought diurnal variations of eye length in human subjects, analogous to those reported in laboratory animals. METHODS Seventeen subjects, ages 7 to 53 (median 16) years and mean spherical equivalent refractive error -0.68 D (range, -3.00 to +1.00 D), underwent axial length measurements at multiple times during the day between 7 AM and 1 AM the following day, using partial c...

Journal: :Investigative ophthalmology & visual science 2010
Scott A Read Michael J Collins Beata P Sander

PURPOSE To investigate the short-term influence of imposed monocular defocus on human optical axial length (the distance from anterior cornea to retinal pigment epithelium) and ocular biometrics. METHODS Twenty-eight young adult subjects (14 myopes, 14 emmetropes) had eye biometrics measured before and 30 and 60 minutes after exposure to monocular (right eye) defocus. Four different monocular...

Journal: :Human molecular genetics 1996
P M Lansdorp N P Verwoerd F M van de Rijke V Dragowska M T Little R W Dirks A K Raap H J Tanke

Vertebrate chromosomes terminate in variable numbers of T2AG3 nucleotide repeats. In order to study telomere repeats at individual chromosomes, we developed novel, quantitative fluorescence in situ hybridization procedures using labeled (C3TA2)3 peptide nucleic acid and digital imaging microscopy. Telomere fluorescence intensity values from metaphase chromosomes of cultured human hematopoietic ...

Journal: :Molecular and Cellular Biology 2000

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