نتایج جستجو برای: leiomyomas

تعداد نتایج: 1254  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2000
S Hague L Zhang M K Oehler S Manek I Z MacKenzie R Bicknell M C Rees

Uterine leiomyomas are the most prevalent benign tumor type in women of reproductive age and are one of the most common indications for hysterectomy. The expression of five angiogenic factors, adrenomedullin (ADM), vascular endothelial growth factor (VEGF), acidic fibroblast growth factor, basic fibroblast growth factor, and platelet-derived endothelial cell growth factor/thymidine phosphorylas...

2014
Mustafa Z. Mahmoud Mohammed Alkhorayef Khalid S. Alzimami Manal Saud Aljuhani Abdelmoneim Sulieman

BACKGROUND High-intensity focused ultrasound (HIFU) is a highly precise medical procedure used locally to heat and destroy diseased tissue through ablation. This study intended to review HIFU in uterine fibroid therapy, to evaluate the role of HIFU in the therapy of leiomyomas as well as to review the actual clinical activities in this field including efficacy and safety measures beside the pub...

Stewart E

Background: Uterine leiomyomas (fibroids) are now known to be highly variable in their clinical behavior and biologic basis. However, the approach to leiomyomas and their effect on fertility, miscarriage and pregnancy complications has been based on location alone. Materials and Methods: This talk with bring together published information on the effect of leiomyomas on reproductive performance ...

Journal: :The Journal of clinical endocrinology and metabolism 1998
T Mizutani A Sugihara K Nakamuro N Terada

Cell proliferation and apoptosis in uterine leiomyoma were investigated during therapy with GnRH agonist (GnRHa). Patients with uterine leiomyomas were injected with 3.75 mg GnRHa (depot leuprolide acetate) at intervals of 4 weeks and underwent hysterectomy or myomectomy at the 2nd, 4th, 8th, 12th, or 16th week of GnRHa therapy. Tissue sections of leiomyomas from these patients and from control...

Journal: :European cytokine network 2004
Małgorzata Wolańska Edward Bańkowski

It is commonly thought that uterine leiomyomas result from hyperstimulation of myometrium by ovarian hormones. Some observations suggest that cytokines and growth factors are intermediate elements through which the ovarian hormones may exert their growth-stimulatory effects on leiomyomas. Human myometrium and uterine leiomyomas of various weights were homogenised and extracted with 1 M acetic a...

Journal: :Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2007
Maritza A Hobson Miklos Z Kiss Tomy Varghese Amy M Sommer Mark A Kliewer James A Zagzebski Timothy J Hall Josephine Harter Ellen M Hartenbach Ernest L Madsen

OBJECTIVE Uterine abnormalities, such as leiomyomas, endometrial polyps, and adenomyosis, are often clinically associated with irregular uterine bleeding. These abnormalities can have similar B-mode characteristics but require different treatment. The objective of this study was to develop diagnostic techniques based on ultrasound strain imaging that would allow in vivo visualization and charac...

Journal: :Journal of vascular and interventional radiology : JVIR 2003
Henri Marret Ana Maria Alonso Jean Philippe Cottier François Tranquart Denis Herbreteau Gilles Body

PURPOSE The purpose of this study was to evaluate the rate of leiomyoma recurrence after uterine artery embolization (UAE) for symptomatic uterine leiomyomas. MATERIALS AND METHODS A prospective study of UAE of uterine leiomyomas has been ongoing at the authors' hospital since 1997. The recurrence rate was assessed in June 2002. Vascular access was obtained via the right common femoral artery...

Journal: :Reproductive biology and endocrinology : RB&E 2007
Qun Pan Xiaoping Luo Nasser Chegini

BACKGROUND Clinical observations indicate that leiomyomas occur more frequently in African Americans compared to other ethnic groups with unknown etiology. To identify the molecular basis for the difference we compared leiomyomas form A. Americans with Caucasians using genomic and proteomic strategies. METHODS Microarray, realtime PCR, 2D-PAGE, mass spectrometry, Western blotting and immunohi...

2016
So Jung Lee Chung Su Hwang Ahrong Kim Kyungbin Kim Kyung Un Choi

Leiomyomas and schwannomas of the gastrointestinal tract (GIT) are mainly comprised of spindle-shaped tumor cells and should always be differentiated from gastrointestinal stromal tumors (GISTs). Mast/stem cell growth factor receptor Kit (KIT) and discovered on GIST-1 (DOG1) are well-known diagnostic markers for the detection of a GIST by immunohistochemical staining. The aim of the present stu...

Journal: :Molecular human reproduction 2002
Xuxia Wu Agneta Blanck Gunnar Norstedt Lena Sahlin Amilcar Flores-Morales

We used a PCR-based subtraction method, representational difference analysis of cDNA (cDNA--RDA), to identify genes with a higher expression in leiomyomas in comparison with the corresponding myometrium during the proliferative phase of the menstrual cycle. Increased expression of the genes for pregnancy-associated plasma protein A (PAPPA), tomoregulin, cellular retinoid acid binding protein 1 ...

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