BACKGROUND The associations of bowel movement frequency and laxative use with cardiovascular disease (CVD) are unclear. METHODS A total of 72 014 subjects (29 668 men and 42 346 women) aged 40 to 79 years, without a history of CVD or cancer, completed a lifestyle questionnaire at baseline between 1988 and 1990 that included information on bowel movement frequency (daily, every 2-3 days, or on...

Introduction. Constipation is a common, bothersome, and potentially dangerous condition among nursing home (NH) patients. Between 50 and 74% of NH patients use laxatives. Objective. To study prevalence and associations of laxative use and constipation using the comprehensive Norwegian version of the Resident Assessment Instrument for Long-Term Care Facilities. Methods. Cross-sectional study. Pa...

A correlation between endoplasmic reticulum (ER) stress and laxative effects was first reported in a constipation model treated with an aqueous extract of Liriope platyphylla (AEtLP) roots. To investigate the correlation between the laxative effect of uridine (Urd) and ER stress response, alterations in the key parameters for ER stress were measured in loperamide (Lop) induced constipation Spra...

BACKGROUND Surreptitious ingestion of laxatives can lead to serious factitious diseases that are difficult to diagnose. Most cases involve ingestion of bisacodyl or senna. Thin layer chromatography (TLC) of urine or stool is the only commercially available test for these laxatives. Such testing is considered highly reliable, but its accuracy in clinical practice is unknown. Our aim was to evalu...

Though others may have found this question hard to swallow (ba-dum-tcchh!), having the strength to be open about this is admirable. Finding yourself with a case of the runs can certainly put a damper on your whole sexual experience. While a semen allergy is one possible cause of dicey bowels, such allergies are quite rare. Perhaps you?ll be relieved to hear that it?s more likely that your diarr...

Tuberculosis is a common disease in India. Mantoux test is used in children for diagnosis of tuberculosis. Seibert first prepared the purified protein derivative (PPD) from heat-concentrated old tuberculin by precipitating protein initially with trichloroacetic acid(l). PPD when diluted is adsorbed by glass and plastic surfaces. To minimize this a small amount of detergent. Tween-80, is added t...

Though others may have found this question hard to swallow (ba-dum-tcchh!), having the strength to be open about this is admirable. Finding yourself with a case of the runs can certainly put a damper on your whole sexual experience. While a semen allergy is one possible cause of dicey bowels, such allergies are quite rare. Perhaps you?ll be relieved to hear that it?s more likely that your diarr...