Between the laminar epidermis and the laminar dermis of laminar region (LR) in equine foot, it can be observed the basement membrane zone (BMZ), which is composed of a basement membrane and its accompaniments like the hemidesmosome and anchoring fibril. Alteration in the BMZ in equine laminitis is possibly related with not only development but also recovery outcome and recurrence of this diseas...

When cereal grain is fed to horses there is a risk of laminitis and it is also common to fmd behavioural changes characterised by chewing wood, eating bedding and grasping (wind sucking). This paper discusses the link between acidity in the gut, as a result of grain feeding, and the risk of laminitis and adverse behaviour. A proportion of the starch consumed as cereal grain passes undigested to...

To confirm ability forming the basement membrane of the regenerated laminar epidermis (rLE) in chronic laminitis, expression of type VII and type XVII collagen mRNAs in the rLE was studied applying sequences of two type of murine collagens. On northern blot analysis, complement DNA (cDNA) probes adjusted from the murine type VII and type XVII collagen could hybridize with the equine mRNAs, and ...

This review paper preSents information on the nutritional and management factors that can predispose dairy animals to laminitis. The suggestions regarding various feeding and management practices that may help in preventing laminitis are also discussed. Lameness in dairy animal is a ~rious problem as it cauSes significant economic loss todairy farmers. The outbreak of laminitis can occur at any...

Abstract Background Laminitis is a common and serve disease which caused by inflammation pathological changes of the laminar junction. However, pathologic mechanism remains unclear. In this study we aimed to investigate gut microbiota metabolomics in oligofructose-induced laminitis horses. Results Animals submitted treatment with oligofructose had lower fecal pH but higher lactic acid, histamin...

Lameness in dairy cows includes many disease conditions, and a systematic approach is required to diagnose the predominant causes and identify the important risk factors. Lameness prevalence can be quantified using locomotion scoring systems. Entire herds can be scored quite easily as they walk access lanes. If lameness prevalence exceeds 15% of the herd, it is important to differentiate the ca...

Background: Laminitis is a common but critical disease that causes severe pain and disability in horses. The etiology and pathogenesis of laminitis remain inconclusive and a multimodal therapeutic approach is generally indicated. Acupuncture has been used as a treatment option; however, the required number of treatments is still controversial due to the lack of objective scient...

Laminitis is one of the most common diseases in horses. It is not only painful for the animal, but also has a significant financial impact on the equine industry. This multifactorial disease affects the connective tissue of the hoof. However, the pathogenesis of laminitis is still not fully understood. Endotoxins, also known as lipopolysaccharides (LPS), and bacterial exotoxins seem to play an ...