Objective. The present study was performed to investigate the effects and mechanisms of miR-99a on LPS-induced endothelial cell inflammation, as well as the regulation of NF-κB on miR-99a production. Methods and Results. ELISA showed that LPS treatment significantly promoted the secretion of inflammatory factors (TNF-α, IL-6, IL-1β, and MCP-1). LPS treatment also inhibited miR-99a production an...

Juan Eusebio Nieremberg gloso una historia legendaria de un rey Dacio en De la devocion y patrocinio san Miguel (Madrid, 1643), cuya fuente original se halla el Llibre dels angels Francesc Eiximenis. La aparecera Nueva Espana edicion pirata. Al texto del jesuita le unira tradicion textual hagiografica postridentina gran aceptacion trasatlantica donde tambien desarrolla imaginario lo transilvano...

biodegradable polysacharyd-based film was developed by incorporating pimpinella affinis essential oil (pao) into methyle cellulose (mc) at level of 0.5%, 1% and 1.5% v/v. then, its antimicrobial activity tested against 7 bacteria include staphylococcus aureus (ptcc 1431), pseudomonas aeruginosa (ptcc 1151), pseudomonas putida(ptcc 1691),esherichia coli (ptcc 3315), listeria monocytogenes (ptcc ...

The present work aims to study a new NADH-cytochrome b5 reductase (cb5r) from Mucor racemosus PTCC 5305. A cDNA coding for cb5r was isolated from a Mucor racemosus PTCC 5305 cDNA library. The nucleotide sequence of the cDNA including coding and sequences flanking regions was determined. The open reading frame starting from ATG and ending with TAG stop codon encoded 228 amino acids and displayed...

Three members of the ERG potassium channel family have been described (ERG1-3 or Kv 11.1-3). ERG1 is by far the best characterized subtype and it constitutes the molecular component of the cardiac I(Kr) current. All three channel subtypes are expressed in neurons but their function remains unclear. The lack of functional information is at least partly due to the lack of specific pharmacological...