PURPOSE To construct a full-thickness biological substitute of the rabbit cornea by tissue engineering. METHODS Ten rabbit corneas were surgically excised, and the three main cell types of the cornea (epithelial, stromal, and endothelial cells) were cultured. Genetic profiling of the cultured cells was performed by RT-PCR for the genes COL8 and KRT12. To develop an organotypic rabbit cornea e...

The rabbit has long been used as a laboratory animal model for developing reproductive and stem cell-related technologies, as well as for studying human disease. The Oct4 transcription factor plays a crucial role in the maintenance and regulation of pluripotency in embryos and stem cells. We constructed a reporter plasmid containing the gene encoding the enhanced green fluorescent protein (EGFP...

abstract objective: to investigate the effect of an anti-inflammatory drug (piroxicam) on the development of fatty streak in rabbits. methods: male rabbits were fed with four types of regimen: a) normal rabbit chow, b) 1% cholesterol diet c) cholesterol diet plus piroxicam, d) normal rabbit chow plus piroxicam. after 12 weeks, the animals were sacrificed and the aorta, as well as the right and ...

ultrasonographic examination of urinary system (kidney and urinary bladder) was conducted in new zealand white rabbit [nzwr] and tolai hare (lepus tolai). ultrasound images of the kidney and urinary bladder were evaluated on fifteen healthy rabbits of new zealand white rabbit and another fifteen tolai hares. the healthy rabbits were 8-12 months old (mean = 9.3 months), of both sexes and weighed...

The present study was conducted to evaluate wound induced in rabbit skin by using alcohols and aqueous extracts of pomegranate seeds. Total flavonoids concentration were estimated high performance liquid chromatography (HPLC). highest recorded ethanol extract. Acute inflammation laboratory animals (rabbits) injecting 0.1mL 2.5% formalin inside the incision. Aqueous seeds an anti-inflammatory he...

Introduction: The ablation technique is one of the important therapeutic interventions for treatment of AV Nodal tachyarrhythmia. Different animal models have been developed to study the effects of ablation on the functional interanodal structure. The aim of the present study was to develop a new model of computer analysis to produce lesions by using direct voltage in isolated perfused rabbi...

In Pierrehumbert (1980) three rising accents are posited for English, H*, L+H* and L*+H, but this three-way contrast has often been disputed. In the present experiment, Minnesotan and Southern Californian speakers read two dialogs which included four levels of emphasis. Emphasis lengthened segmental duration, raised the scaling of all tones and delayed H alignment in L+H*. Independently of emph...