Abstract Mycoplasma pulmonis and muris infections have been associated with several diseases in conventionally housed laboratory rat and mice colonies. In naturally infected of mycoplasma pulmonis in mice and rat colonies, the respiratory organ appears to be the favored site of colonization; so, it was not surprising to see that infection spread from the site of urogenital tract to the respirat...

objective: to evaluate the potentiality of ovcar–3 cell line of ovarian adenocarcinoma as a xenograft model for ovarian adenocarcinoma in nude mice. materials and methods: the cell line isolated from advanced human ovarian adenocarcinoma, were inoculated to eight nude mice and two months later. established tumors were transferred to pathology laboratory to be prepared by h&e; staining and immun...

the susceptibility of various strains of mice to infection by leishmania tropica (major) was recently studied in this laboratory. the infection in a/j, c3h, cba, akr/j, akr/cu, and c57b1 mice (the semi resistant strains) remained cutaneous and the animals recovered within 4-6 months. however balb/c mice developed generalized infection after two months of exposure resulting in death 3-4 months l...

This paper examines the relationship between performance and size of R&D laboratories operated abroad. Based on a theoretical argument, the paper proposes a concave relationship between laboratory size and performance, as well as a linear relationship between firm learning and laboratory performance. Empirical tests with 129 laboratories established by 27 multinational companies in the pharmace...

In Melendez-Diaz v. Massachusetts, 129 S.Ct. 2527 (2009), the United States Supreme Court resolved a question that had divided the lower courts in the wake of Crawford v. Washington, 541 U.S. 36 (2004). The Melendez-Diaz Court held by a 5-4 vote that forensic laboratory reports are testimonial for purposes of the Confrontation Clause of the Sixth Amendment. Therefore, even if the jurisdiction’s...

Abstract Fungi are found ubiquitously in the mammalian gut however role of commensal fungi host is poorly understood. Laboratory mice used to model host-fungi interactions due ultra-clean housing they do not harbor fungi. The human fungus Candida albicans widely studied dissect host-commensal prior dysbiosis bacteria required colonize laboratory mice. Insights from such forced host-fungal unsui...