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Linum spp. from section Syllinum are promising for the production of aryltetralin lignans like podophyllotoxin (PTOX) and 6-methoxypodophyllotoxin (MPTOX). MPTOX is a PTOX congener that has cytotoxic activity comparable with PTOX. In this study root cultures of Linum Bungei from section Dasyllinum, L. strictum from section Linastrum, L. album, L. mucronatum ssp. mucronatum and L. nodiflorum fro...
Introduction: The present study aimed to investigate the protective effects of Pimpinella anisum L. ethanolic and aqueous extracts on L-asparaginase- associated hepatotoxicity in rats using histopathological and specific 99mTc-Phytate biodistribution studies. Materials and Methods: 60 female rats were divided into 9 treatment groups including L-asparaginase group, Aqueous extract (100 and 200 m...
BACKGROUND Acid stress impacts the persistence of lactobacilli in industrial sourdough fermentations, and in intestinal ecosystems. However, the contribution of glutamate to acid resistance in lactobacilli has not been demonstrated experimentally, and evidence for the contribution of acid resistance to the competitiveness of lactobacilli in sourdough is lacking. It was therefore the aim of this...
We evaluated bronopol as a practical alternative anti-fungal agent to malachite green for use in hatcheries. Repeated exposure everyday, just after fertilization to the stage of eggs showing eye development to 50 mg/L and 100 mg/L bronopol for 30 min showed an efficacy comparable to 0 mg/L (control) for the inhibition of fungal infection in rainbow trout (Oncorhynchus mykiss) eggs. The 100 mg/L...
O objetivo do trabalho foi avaliar o uso de solventes verdes na extração compostos fenólicos da casca abacate. Foram testados 7 solventes: 1) etanol (100%); 2) (50%) + água destilada (50%); 3) 4) ácido lático 5) 6) glicerina 7) (50%). Para os testes foram usadas aproximadamente 5 gramas abacate e 100 mL solvente testado. dos totais, a apresentou maior potencial com 609,9 mg EAG/L, havendo varia...
OBJECTIVE Testicular feminised (Tfm) mice express a non-functional androgen receptor, and also have reduced levels of circulating testosterone. Recent studies support a cardio-protective role for testosterone since it elicits systemic and pulmonary vasodilatation. The aim of the present study was to determine whether androgen insensitivity and hypotestosteronaemia in the Tfm mouse are associate...
Our recent study indicated that, in the dorsal motor nucleus of the vagus (DMV), the N-methyl-D-aspartic acid (NMDA) receptor-nitric oxide (NO)-cGMP pathway participated in the regulation of gallbladder motility in rabbits. Oxytocin (OT) is involved as a neurotransmitter in autonomic regulation. The aim of the present experiments is to investigate the effect of OT microinjected into DMV on the ...
The aim of this study was to investigate the chemical characteristics of seeds in two cultivated bitter landraces of Lupinus albus and two wild Lupinus angustifolius types in Mediterranean environment (Hatay, southern Turkey). Fat quantity and fatty acid quality were considerably different depending on the genotype. L. albus showed the higher oil content (74.0-85.1 g/kg), saturated fatty acids ...
Ahrén, Bo, and Peter J. Havel. Leptin inhibits insulin secretion induced by cellular cAMP in a pancreatic B cell line (INS-1 cells). Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R959–R966, 1999.—The effect of leptin on insulin secretion is controversial due to conflicting results in the literature. In the present study, we incubated insulinproducing rat insulinoma INS-1 cells...
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